2,5-Bis(trifluoromethyl)benzenesulfonyl chloride
2,5-Bis(trifluoromethyl)benzenesulfonyl chloride (CAS: 351003-22-0) is an organosulfur compound with the molecular formula (CF3)2C6H3SO2Cl and a molecular weight of 312.62 g/mol. This compound functions as a versatile building block in organic synthesis, particularly in the introduction of the 2,5-bis(trifluoromethyl)benzenesulfonyl group into various molecules. Its reactive sulfonyl chloride moiety facilitates its use in derivatisation and the construction of more complex chemical structures.
- Synonyms
- (CF3)2C6H3SO2Cl
Organic Synthesis Intermediate
This compound serves as a key intermediate in the synthesis of novel organic molecules. The presence of two trifluoromethyl groups on the benzene ring imparts unique electronic properties, making it valuable for creating specialised derivatives.
Building Block for Pharmaceutical Research
It can be employed in the development of new pharmaceutical candidates. The unique structural features introduced by the bis(trifluoromethyl)benzenesulfonyl moiety may influence biological activity and physicochemical properties of potential drug molecules.
Reagent in Chemical Derivatisation
2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is utilised as a derivatising agent to modify the properties of other compounds, aiding in analysis or tuning reactivity in complex synthetic pathways.
| Molecular weight | 312.62 |
|---|---|
| Linear formula | (CF3)2C6H3SO2Cl |
| Assay | 97% |
| Melting point | 59-63 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride used for?
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2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly for introducing the 2,5-bis(trifluoromethyl)benzenesulfonyl group into other molecules for pharmaceutical research and chemical derivatisation.
What is the CAS number and molecular formula for 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride?
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The CAS number for 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is 351003-22-0, and its molecular formula is (CF3)2C6H3SO2Cl.
What grade and purity does Tech Serve Solutions supply for 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride?
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Tech Serve Solutions supplies 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride with a purity of 97% (assay). This product is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeial standard.
How should 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride be handled safely?
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This compound is classified as corrosive and can cause severe skin burns and eye damage (H314). Handling requires stringent safety precautions, including the use of appropriate personal protective equipment such as eyeshields, face shields, chemical-resistant gloves, and respiratory protection (e.g., N100 respirators). Work should be conducted in a well-ventilated area or fume hood.
How is 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride packed and shipped?
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2,5-Bis(trifluoromethyl)benzenesulfonyl chloride is packed and shipped in compliance with transportation regulations, identified as UN 3261, Class 8, Packing Group II, suitable for corrosive materials.
How can I request a quote or sample of 2,5-Bis(trifluoromethyl)benzenesulfonyl chloride?
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To request a quote or a sample, please use the contact form on our website or email our sales department directly. Please include the product name and CAS number for prompt service.
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