2,5-Bis(trifluoromethyl)benzaldehyde
2,5-Bis(trifluoromethyl)benzaldehyde (CAS 395-64-2) is a fluorinated aromatic aldehyde with a molecular weight of 242.12 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for introducing the bis(trifluoromethyl)phenyl moiety into complex molecules. Its reactivity as an aldehyde makes it useful in various chemical transformations, contributing to the development of novel materials and pharmaceutical intermediates.
- Synonyms
- (CF3)2C6H3CHO
Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. The presence of two trifluoromethyl groups offers unique electronic and steric properties.
Fluorinated Compound Development
Serves as a precursor for creating advanced fluorinated materials and speciality chemicals. Its structure facilitates the incorporation of fluorine into target compounds.
Pharmaceutical Research
Employed in medicinal chemistry research for the synthesis of potential drug candidates. Fluorine substitution can modulate pharmacokinetic and pharmacodynamic properties.
| Molecular weight | 242.12 |
|---|---|
| Linear formula | (CF3)2C6H3CHO |
| Assay | 97% |
| Boiling point | 137 °C(lit.) |
| Density | 1.468 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.421(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 69 °C / 156.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Bis(trifluoromethyl)benzaldehyde used for?
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2,5-Bis(trifluoromethyl)benzaldehyde is primarily used as a building block in organic synthesis, particularly for introducing bis(trifluoromethyl)phenyl groups into molecules for pharmaceutical research and the development of speciality chemicals.
What is the CAS number and formula for 2,5-Bis(trifluoromethyl)benzaldehyde?
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The CAS number is 395-64-2, and the linear formula is (CF3)2C6H3CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Bis(trifluoromethyl)benzaldehyde with a minimum purity of 97%. This product is not supplied as USP, BP, or EP grade.
How should 2,5-Bis(trifluoromethyl)benzaldehyde be handled safely?
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Handling requires caution due to potential skin, eye, and respiratory irritation (H315, H319, H335). Use appropriate personal protective equipment, including safety goggles, gloves, and a respirator, in a well-ventilated area.
How is 2,5-Bis(trifluoromethyl)benzaldehyde packed and shipped?
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Products are carefully packed according to international shipping regulations and can be exported globally by Tech Serve Solutions.
How can I request a sample or quote for 2,5-Bis(trifluoromethyl)benzaldehyde?
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Please contact our sales team or use the online enquiry form to request a sample or a quotation for 2,5-Bis(trifluoromethyl)benzaldehyde.
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