2,5-Bis(trifluoromethyl)phenylacetic acid
2,5-Bis(trifluoromethyl)phenylacetic acid (CAS 302912-02-3) is a speciality organic compound with the linear formula (CF3)2C6H3CH2CO2H and a molecular weight of 272.14. It is primarily utilised as a building block in organic synthesis. This carboxylic acid derivative features two trifluoromethyl groups on the phenyl ring, making it a valuable intermediate for introducing fluorinated moieties into more complex molecules, particularly in the development of pharmaceuticals and advanced materials.
- Synonyms
- (CF3)2C6H3CH2CO2H

Organic Synthesis Intermediate
Serves as a key building block in the synthesis of novel organic compounds. Its unique structure, featuring electron-withdrawing trifluoromethyl groups, allows for specific reactivity in various chemical transformations.
Pharmaceutical Research
Utilised in the research and development of new pharmaceutical agents. The incorporation of trifluoromethyl groups can significantly influence a drug candidate's pharmacokinetic properties, such as metabolic stability and lipophilicity.
Materials Science
Employed in the creation of advanced materials, where the presence of fluorine atoms can impart desirable properties like thermal stability, chemical resistance, and altered surface characteristics.
| Molecular weight | 272.14 |
|---|---|
| Linear formula | (CF3)2C6H3CH2CO2H |
| Assay | 97% |
| Melting point | 95-98 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Bis(trifluoromethyl)phenylacetic acid used for?
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2,5-Bis(trifluoromethyl)phenylacetic acid is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and materials science, owing to its unique fluorinated structure.
What is the CAS number and chemical formula for 2,5-Bis(trifluoromethyl)phenylacetic acid?
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The CAS number is 302912-02-3, and the linear formula is (CF3)2C6H3CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,5-Bis(trifluoromethyl)phenylacetic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2,5-Bis(trifluoromethyl)phenylacetic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Ensure good ventilation. Avoid breathing dust. This compound is classified as causing skin irritation, serious eye irritation, and respiratory irritation (H315-H319-H335).
Is 2,5-Bis(trifluoromethyl)phenylacetic acid a controlled substance?
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Based on the provided data, there is no indication that 2,5-Bis(trifluoromethyl)phenylacetic acid is a controlled substance.
How is this chemical packed and shipped?
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This chemical is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions is a global supplier and exporter.
How can I request a quote or sample?
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To request a quote or sample of 2,5-Bis(trifluoromethyl)phenylacetic acid, please contact our sales team through the website or by phone.
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