4-Hydroxyquinazoline
4-Hydroxyquinazoline (CAS: 491-36-1; Formula: C8H6N2O) is a heterocyclic organic compound with a molecular weight of 146.15 g/mol. This quinazoline derivative is recognised for its utility as a building block in chemical synthesis and its relevance in cell biology research. It serves as a valuable intermediate in the development of novel compounds, particularly within the fields of medicinal chemistry and drug discovery.
- IUPAC
- 4-Quinazolinol

Chemical Synthesis Intermediate
4-Hydroxyquinazoline acts as a key building block in organic synthesis, enabling the construction of more complex molecular architectures. Its quinazoline core is a prevalent scaffold in medicinal chemistry.
Research and Development
Utilised in laboratory settings for exploring new chemical entities and investigating biological pathways. Its structure makes it suitable for structure-activity relationship studies in drug discovery programmes.
Bioactive Compound Precursor
Serves as a precursor for synthesising various bioactive molecules. The quinazoline motif is found in numerous pharmaceuticals with diverse therapeutic applications.
| Molecular weight | 146.15 |
|---|---|
| Empirical formula | C8H6N2O |
| Assay | 98% |
| Melting point | 216-219 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Parp2(11546) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxyquinazoline used for?
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4-Hydroxyquinazoline is primarily used as a building block in chemical synthesis and in research and development for creating novel bioactive compounds. It is a precursor for various molecules, particularly in medicinal chemistry and drug discovery.
What is the CAS number and formula for 4-Hydroxyquinazoline?
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The CAS number for 4-Hydroxyquinazoline is 491-36-1, and its empirical formula (Hill notation) is C8H6N2O.
What grade and purity does Tech Serve Solutions supply for 4-Hydroxyquinazoline?
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Tech Serve Solutions supplies 4-Hydroxyquinazoline with a minimum assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should 4-Hydroxyquinazoline be handled safely?
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4-Hydroxyquinazoline is classified with warning signal word and hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment: a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation and avoid dust formation.
Is 4-Hydroxyquinazoline a controlled substance?
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The provided data does not indicate that 4-Hydroxyquinazoline (CAS: 491-36-1) is a controlled substance.
How is 4-Hydroxyquinazoline packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports fine chemicals like 4-Hydroxyquinazoline according to international regulations for chemical transport. Specific packaging details can be provided upon request.
How can I request a sample or quote for 4-Hydroxyquinazoline?
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To request a sample or a quote for 4-Hydroxyquinazoline, please contact the Tech Serve Solutions sales team through our website or via the contact information provided.
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