2,5-Bis(trimethylsilyl)thiazole
2,5-Bis(trimethylsilyl)thiazole (CAS: 79265-34-2) is a heterocyclic compound with the molecular formula C9H19NSSi2 and a molecular weight of 229.49 g/mol. This organosilicon derivative of thiazole serves as a valuable building block in organic synthesis. It is particularly useful in the construction of more complex molecules within the pharmaceutical and chemical research sectors, leveraging its unique silicon-thiazole structure for further chemical transformations.
- Synonyms
- C9H19NSSi2

Heterocyclic Synthesis
2,5-Bis(trimethylsilyl)thiazole functions as a key intermediate in the synthesis of diverse heterocyclic compounds. Its silyl groups can be selectively functionalised or removed, enabling controlled elaboration of the thiazole core.
Pharmaceutical Research
This compound is employed as a building block in medicinal chemistry for the development of novel drug candidates. The thiazole moiety is present in numerous biologically active molecules, making this reagent a useful tool for creating new pharmaceutical leads.
Materials Science
Organosilicon compounds, including derivatives like 2,5-Bis(trimethylsilyl)thiazole, can find applications in materials science, potentially contributing to the development of new polymers or specialised materials due to the unique properties imparted by silicon.
| Molecular weight | 229.49 |
|---|---|
| Empirical formula | C9H19NSSi2 |
| Storage temperature | 2-8°C |
| Melting point | 46-56 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Bis(trimethylsilyl)thiazole used for?
+
2,5-Bis(trimethylsilyl)thiazole is primarily used as a building block in organic synthesis, particularly for the construction of complex heterocyclic compounds and in pharmaceutical research.
What is the CAS number and molecular formula for 2,5-Bis(trimethylsilyl)thiazole?
+
The CAS number is 79265-34-2 and the empirical formula (Hill notation) is C9H19NSSi2.
What grade and purity does Tech Serve Solutions supply for 2,5-Bis(trimethylsilyl)thiazole?
+
Tech Serve Solutions supplies 2,5-Bis(trimethylsilyl)thiazole as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia standard unless explicitly stated in the product specifications.
How should 2,5-Bis(trimethylsilyl)thiazole be handled safely?
+
Handle 2,5-Bis(trimethylsilyl)thiazole with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation to avoid respiratory irritation (H335). It is irritating to the skin (H315) and eyes (H319). Avoid dust formation and inhalation.
Is 2,5-Bis(trimethylsilyl)thiazole shipped internationally?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,5-Bis(trimethylsilyl)thiazole. We can facilitate international shipments.
How can I request a sample or quote for 2,5-Bis(trimethylsilyl)thiazole?
+
To request a sample or a quote for 2,5-Bis(trimethylsilyl)thiazole, please contact our sales department through the website or by phone, providing your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis