2,3,4,5-Tetrafluorobenzoyl chloride
2,3,4,5-Tetrafluorobenzoyl chloride (CAS 94695-48-4, C7H3ClF4O) is a fluorinated aryl compound with a molecular weight of 212.53 g/mol. It functions as a reactive acyl chloride, often employed as a key building block in organic synthesis. Its utility lies in introducing the tetrafluorobenzoyl moiety into various molecular structures, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials where fluorination can impart unique properties.
- Synonyms
- 2,3,4,5-Tetrafluorobenzoyl chloride5-Tetrafluorobenzoyl chlorideHC6F4COCl

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), where the fluorinated benzoyl group can influence drug metabolism, lipophilicity, and binding affinity.
Agrochemical Development
Serves as a precursor for novel pesticides and herbicides, leveraging the stability and biological activity often associated with fluorinated organic compounds.
Material Science Research
Incorporated into the design of advanced materials, such as liquid crystals or polymers, where its specific electronic and structural characteristics can be advantageous.
Organic Synthesis Reagent
Acts as a versatile acylating agent for introducing the 2,3,4,5-tetrafluorobenzoyl group in complex organic molecules, facilitated by the reactive acid chloride functionality.
| Molecular weight | 212.53 |
|---|---|
| Linear formula | HC6F4COCl |
| Assay | 98% |
| Density | 1.58 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4787(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3,4,5-Tetrafluorobenzoyl chloride used for?
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2,3,4,5-Tetrafluorobenzoyl chloride is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It serves as a reactive intermediate for introducing the tetrafluorobenzoyl moiety into target molecules.
What is the CAS number and molecular formula for 2,3,4,5-Tetrafluorobenzoyl chloride?
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The CAS number is 94695-48-4 and the molecular formula is C7H3ClF4O.
What grade and purity does Tech Serve Solutions supply for 2,3,4,5-Tetrafluorobenzoyl chloride?
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Tech Serve Solutions supplies 2,3,4,5-Tetrafluorobenzoyl chloride with an assay of 98%. This product is supplied for research and development or further manufacturing purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2,3,4,5-Tetrafluorobenzoyl chloride be handled safely?
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2,3,4,5-Tetrafluorobenzoyl chloride is a Danger product (GHS05) that causes severe skin burns and eye damage (H314). Handle with extreme caution, wearing full protective equipment including a face shield, chemical-resistant gloves, and safety goggles. Ensure adequate ventilation, and use a suitable respirator filter (e.g., ABEK type). In case of contact, follow emergency procedures.
Is 2,3,4,5-Tetrafluorobenzoyl chloride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,3,4,5-Tetrafluorobenzoyl chloride. We handle all necessary export documentation and logistics for international customers.
How can I request a quote or sample of 2,3,4,5-Tetrafluorobenzoyl chloride?
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To request a quote or a sample, please use the contact form on our website or call our sales department. Our team will be pleased to assist you with your inquiry.
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