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2,3,4,5-Tetrafluoroaniline

CAS 5580-80-3HC6F4NH2Chemical Synthesis

2,3,4,5-Tetrafluoroaniline (CAS 5580-80-3), with the molecular formula HC6F4NH2 and a molecular weight of 165.09 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis, particularly for creating complex fluorinated molecules. Its primary application lies in the synthesis of polyfluorinated quinolines, contributing to advancements in materials science and medicinal chemistry.

Synonyms
5-TetrafluoroanilineHC6F4NH2
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2,3,4,5-Tetrafluoroaniline (HC6F4NH2) — chemical structure, CAS 5580-80-3; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisFluorinated Building BlocksNitrogen CompoundsOrganic Building Blocks
01 /Applications

Synthesis of Polyfluorinated Quinolines

2,3,4,5-Tetrafluoroaniline is a key intermediate in the synthesis of polyfluorinated quinoline derivatives. These compounds are of interest for their potential applications in pharmaceuticals and advanced materials.

Fluorinated Aromatic Building Block

As a fluorinated aryl building block, this aniline derivative offers a versatile platform for introducing tetrafluorinated phenyl rings into various organic structures, enabling the development of novel chemical entities.

Organic Synthesis Intermediate

This compound is utilized in complex organic synthesis pathways, providing a reactive amine group on a highly fluorinated benzene ring. It is suitable for research and development in synthetic chemistry.

02 /Properties
Molecular weight165.09
Linear formulaHC6F4NH2
Assay98%
Boiling point78 °C/13 mmHg(lit.)
Application2,3,4,5-Tetrafluoroaniline can be used in the synthesis of polyfluorinated quinolines1.
Melting point27-29 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point79 °C / 174.2 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-27-36/37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
5580-80-3
MDL number
MFCD00025153
PubChem substance
24846436
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,3,4,5-Tetrafluoroaniline used for?

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2,3,4,5-Tetrafluoroaniline is primarily used as a building block in organic synthesis, notably for the preparation of polyfluorinated quinolines.

What is the CAS number and formula for 2,3,4,5-Tetrafluoroaniline?

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The CAS number is 5580-80-3, and the linear formula is HC6F4NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2,3,4,5-Tetrafluoroaniline with a minimum assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.

What are the primary safety concerns when handling 2,3,4,5-Tetrafluoroaniline?

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2,3,4,5-Tetrafluoroaniline is classified as a warning substance with hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Appropriate personal protective equipment, including dust masks (type N95 US), eyeshields, and gloves, should be used. Ensure adequate ventilation.

How is 2,3,4,5-Tetrafluoroaniline supplied and exported?

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Tech Serve Solutions, as a specialist global supplier and exporter, ensures that 2,3,4,5-Tetrafluoroaniline is packaged and shipped according to international regulations for chemical transport.

How can I request a quote or sample of 2,3,4,5-Tetrafluoroaniline?

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To request a quote or a sample of 2,3,4,5-Tetrafluoroaniline, please contact the Tech Serve Solutions sales team through our website or direct inquiry channels.

Need 2,3,4,5-Tetrafluoroaniline in a specific grade or volume?