2,2,3,3-Tetrafluoro-1-propanol
2,2,3,3-Tetrafluoro-1-propanol (CAS 76-37-9) is a fluorinated alcohol with the molecular formula CHF2CF2CH2OH and a molecular weight of 132.06 g/mol. This compound is recognised for its unique properties stemming from the presence of fluorine atoms. It serves as a valuable building block and intermediate in organic synthesis, particularly in the development of fluorinated materials and pharmaceuticals.
- Synonyms
- 3-Tetrafluoro-1-propanolCHF2CF2CH2OH

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of various fluorinated organic compounds. Its structure allows for the introduction of difluoromethyl and related fluorinated moieties into target molecules.
Fluorinated Building Block
Serves as a versatile building block for creating more complex fluorinated structures. It is employed in research and development for novel material science and pharmaceutical applications.
Specialty Chemical Synthesis
Applied in the synthesis of specialty chemicals where fluorination is required to impart specific properties such as altered reactivity, lipophilicity, or stability.
| Molecular weight | 132.06 |
|---|---|
| Linear formula | CHF2CF2CH2OH |
| Assay | 98% |
| Boiling point | 107-109 °C(lit.) |
| Density | 1.48 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.321(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H319Causes serious eye irritation
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 43 °C / 109.4 °F |
| Transport (UN / ADR) | UN 1986 3/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,3,3-Tetrafluoro-1-propanol used for?
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2,2,3,3-Tetrafluoro-1-propanol is primarily used as an intermediate and building block in organic synthesis, particularly for creating fluorinated compounds for materials science and pharmaceutical research.
What are the CAS number and chemical formula for 2,2,3,3-Tetrafluoro-1-propanol?
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The CAS number is 76-37-9, and the linear chemical formula is CHF2CF2CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,3,3-Tetrafluoro-1-propanol with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards unless explicitly stated in the product specifications.
What are the primary safety concerns when handling 2,2,3,3-Tetrafluoro-1-propanol?
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2,2,3,3-Tetrafluoro-1-propanol is a flammable liquid and vapour (H226) and is toxic if inhaled (H331). It also causes serious eye irritation (H319). Appropriate personal protective equipment, including respiratory protection, gloves, and eye protection, must be used, and handling should occur in a well-ventilated area.
How is 2,2,3,3-Tetrafluoro-1-propanol packed, shipped, and exported?
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2,2,3,3-Tetrafluoro-1-propanol is available for global export. Packaging adheres to relevant transport regulations for hazardous materials, including UN 1986 classification. Contact TSS for specific shipping details.
How can I request a sample or quote for 2,2,3,3-Tetrafluoro-1-propanol?
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To request a sample or obtain a quotation for 2,2,3,3-Tetrafluoro-1-propanol, please contact our sales team via the website or direct inquiry.
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