2,2,3,3-Tetrafluoro-1,4-butanediol
2,2,3,3-Tetrafluoro-1,4-butanediol (CAS: 425-61-6) is a fluorinated organic building block with the molecular formula HOCH₂CF₂CF₂CH₂OH and a molecular weight of 162.08 g/mol. This polyol is characterised by its tetrafluorinated core, making it a valuable intermediate in organic synthesis. It serves as a reactant in the development of specialised materials, including enzymic synthesis of silicone fluorinated aliphatic polyester amides, contributing to advancements in material science and chemical research.
- IUPAC
- 2,2,3,3-Tetrafluorobutanediol,NSC 95113,Tetrafluoro-1,4-butanediol
- Synonyms
- 3-Tetrafluoro-1,4-butanediolTetrafluoro-1,4-butanediolHOCH2CF2CF2CH2OHNSC 95113

Fluorinated Polyesters and Amides
Serves as a key reactant in the synthesis of specialised fluorinated aliphatic polyester amides. Its unique structure allows for the incorporation of fluorine into polymer backbones, imparting desirable properties such as chemical resistance and thermal stability.
Advanced Material Synthesis
Utilised as a building block in organic synthesis for creating novel fluorinated compounds. It enables the development of materials with tailored properties for demanding applications in various industries.
Research and Development
A versatile reagent for chemical synthesis and research purposes. It is employed in academic and industrial R&D settings to explore new chemical pathways and material functionalities.
| Molecular weight | 162.08 |
|---|---|
| Linear formula | HOCH2CF2CF2CH2OH |
| Boiling point | 110-112 °C/13 mmHg(lit.) |
| Application | Reactant for:Enzymic synthesis of silicone fluorinated aliphatic polyester amides1 |
| Melting point | 77-82 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,3,3-Tetrafluoro-1,4-butanediol used for?
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2,2,3,3-Tetrafluoro-1,4-butanediol is used as a reactant in the enzymic synthesis of silicone fluorinated aliphatic polyester amides and as a building block in organic synthesis for creating novel fluorinated compounds.
What are the CAS number and molecular formula?
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The CAS number for 2,2,3,3-Tetrafluoro-1,4-butanediol is 425-61-6, and its linear formula is HOCH₂CF₂CF₂CH₂OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,3,3-Tetrafluoro-1,4-butanediol as a technical/research grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
What are the safety precautions for handling 2,2,3,3-Tetrafluoro-1,4-butanediol?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The substance has a WGK Germany rating of 3, indicating it is hazardous to water.
How is 2,2,3,3-Tetrafluoro-1,4-butanediol packed and exported?
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Tech Serve Solutions exports chemicals globally, ensuring appropriate packaging that complies with international shipping regulations. Specific packaging details will be provided upon order confirmation.
How can I request a sample or quote for 2,2,3,3-Tetrafluoro-1,4-butanediol?
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To request a sample or a quote, please contact our sales department through the enquiry form on our website or by calling our customer service line.
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