2,2,3,3,4,4-Hexafluoro-1,5-pentanediol
2,2,3,3,4,4-Hexafluoro-1,5-pentanediol (CAS: 376-90-9) is a specialized fluorinated organic building block with the linear formula HOCH2(CF2)3CH2OH and a molecular weight of 212.09 g/mol. This compound serves as a key precursor in the synthesis of unique per- and polyfluoroethers and cyclic/acyclic polyfluorosiloxanes. Its distinct fluorinated structure makes it valuable for advanced material science and chemical research applications.
- Synonyms
- 3,4,4-Hexafluoro-1,5-pentanediol376-90-9HOCH2(CF2)3CH2OH

Precursor for Polyfluoroethers
Utilised in the preparation of per- and polyfluoroethers, valuable materials with unique thermal and chemical properties.
Synthesis of Polyfluorosiloxanes
Serves as a building block for both cyclic and acyclic polyfluorosiloxanes, contributing to the development of novel fluorinated polymers.
Advanced Material Science
Its fluorinated nature makes it an important intermediate for creating materials with enhanced chemical resistance and thermal stability.
Chemical Synthesis Research
A versatile fluorinated building block employed in organic synthesis for researchers developing new fluorinated compounds and materials.
| Molecular weight | 212.09 |
|---|---|
| Linear formula | HOCH2(CF2)3CH2OH |
| Assay | 98% |
| Boiling point | 111.5 °C/10 mmHg(lit.) |
| Application | Used for the preparation of cyclic and acyclic polyfluorosiloxanes as precursors to per- and polyfluoroethers.1,2 |
| Melting point | 78-81 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol used for?
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It is used for the preparation of cyclic and acyclic polyfluorosiloxanes as precursors to per- and polyfluoroethers.
What is the CAS number and formula for 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol?
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The CAS number is 376-90-9 and the linear formula is HOCH2(CF2)3CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol with an assay of 98%. This product is not supplied as USP, BP, EP or pharmaceutical grade.
How should 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as harmful if swallowed (H302).
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, exporting this product worldwide.
How can I request a sample or quote for 2,2,3,3,4,4-Hexafluoro-1,5-pentanediol?
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Please contact our sales team to request a sample or a detailed quotation for this product.
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