Pentamethylcyclopentadienylrhodium(III) chloride dimer
Pentamethylcyclopentadienylrhodium(III) chloride dimer (CAS: 12354-85-7; Formula: [Rh(C5Me5)Cl2]2; MW: 618.08) is a rhodium-based precatalyst widely employed in modern synthetic chemistry. It is particularly valued for its role in C-H activation and various catalytic transformations. This compound facilitates complex bond formations and functionalisations, making it an essential reagent for advanced chemical synthesis and inorganic chemistry research.
- IUPAC
- 1,3-Cyclopentadiene, 1,2,3,4,5-pentamethyl-, rhodium complex,Bis(dichloro(pentamethylcyclopentadienyl)rhodium),Bis(pentamethylcyclopentadienylrhodium dichloride),Dichloro(pentamethylcyclopentadienyl)rhodium(II) dimer,Tetrachlorobis(pentamethylcyclopentadienyl)dirhodium
- Synonyms
- Bis(dichloro(pentamethylcyclopentadienyl)rhodium),Bis(pentamethylcyclopentadienylrhodium dichloride),Dichloro(pentamethylcyclopentadienyl)rhodium(II) dimer,Tetrachlorobis(pentamethylcyclopentadienyl)dirhodium
![Pentamethylcyclopentadienylrhodium(III) chloride dimer ([Rh(C5Me5)Cl2]2) — chemical structure, CAS 12354-85-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12354-85-7.png&w=3840&q=75)
C-H Activation Catalysis
This rhodium complex serves as a precatalyst for activating and functionalising C-H bonds, enabling direct ortho-olefination of phenol derivatives and oxidative ortho-acylation of benzamides.
Oxidative Olefination Reactions
It catalyses oxidative olefination reactions, a key process for introducing carbon-carbon double bonds into organic molecules.
Bond Cleavage and Functionalisation
The dimer acts as a catalyst for the C-C bond cleavage of secondary alcohols and facilitates amidation and reductive alkylation reactions.
Catalysis for Complex Synthesis
Used in oxidative annulation of pyridines and other processes, this rhodium precatalyst supports the synthesis of complex organic frameworks.
| Molecular weight | 618.08 |
|---|---|
| Linear formula | [Rh(C5Me5)Cl2]2 |
| Application | Umicore Precatalysts for Asymmetric and Cross-Coupling CatalysisCatalyst for:• Oxidative olefination reactions1• C-C bond cleavage of secondary alcohols2• Ortho C-H olefination of phenol derivatives3• Oxidative annulation of pyridines4• Oxidative ortho-acylation of benzamides with aldehydes via direct functionalization of the sp2 C-H bond5• Amidation reactions6• Reductive alkylation reactions7 |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentamethylcyclopentadienylrhodium(III) chloride dimer used for?
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This compound is used as a precatalyst for various transformations including oxidative olefination reactions, C-C bond cleavage, ortho C-H olefination, oxidative annulation of pyridines, oxidative ortho-acylation of benzamides, amidation reactions, and reductive alkylation reactions.
What is the CAS number and formula for Pentamethylcyclopentadienylrhodium(III) chloride dimer?
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The CAS number is 12354-85-7 and the formula is [Rh(C5Me5)Cl2]2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research or technical grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
How should Pentamethylcyclopentadienylrhodium(III) chloride dimer be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust, and ensure adequate ventilation as it is harmful if swallowed, in contact with skin, or inhaled, and causes skin and eye irritation.
Is Pentamethylcyclopentadienylrhodium(III) chloride dimer a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions adheres to stringent packaging, shipping, and export regulations for all its chemical products, ensuring safe and compliant delivery worldwide.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales team through the website or direct inquiry channels, providing the product name and CAS number.
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