2-(2-Chloroethoxy)ethanol
2-(2-Chloroethoxy)ethanol (CAS 628-89-7) is an organic compound with the linear formula ClCH2CH2OCH2CH2OH and a molecular weight of 124.57 g/mol. This chemical, also known as diethylene glycol monochlorohydrin, serves as a valuable intermediate in organic synthesis. It is primarily utilised in the chemical industry for the preparation of various complex molecules and building blocks.
- IUPAC
- Diethylene glycol monochlorohydrin
- Synonyms
- Diethylene glycol monochlorohydrin
Organic Synthesis Intermediate
2-(2-Chloroethoxy)ethanol functions as a key building block in multi-step organic syntheses. Its reactive chloroethoxy and hydroxyl groups allow for versatile derivatisation, contributing to the creation of more complex molecular structures.
Pharmaceutical Intermediate
This compound has been employed in the synthesis pathway of pharmaceutical agents, notably contributing to the production of quetiapine, an important antipsychotic medication.
Precursor for Speciality Chemicals
It is used in the synthesis of specific organic compounds, such as o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal and 2-(2-azidoethoxy)ethanol, enabling the development of niche chemical products.
| Molecular weight | 124.57 |
|---|---|
| Linear formula | ClCH2CH2OCH2CH2OH |
| Assay | 99% |
| Boiling point | 79-81 °C/5 mmHg(lit.) |
| Density | 1.18 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.452(lit.) |
| Application | 2-(2-Chloroethoxy)ethanol was used in the synthesis of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal1, quetiapine (an antipsychotic drug)2 and 2-(2-azidoethoxy)ethanol3. |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(2-Chloroethoxy)ethanol used for?
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2-(2-Chloroethoxy)ethanol is primarily used as an intermediate in organic synthesis, including the production of pharmaceuticals and speciality chemicals.
What are the CAS number and formula for 2-(2-Chloroethoxy)ethanol?
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The CAS number for 2-(2-Chloroethoxy)ethanol is 628-89-7, and its linear formula is ClCH2CH2OCH2CH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(2-Chloroethoxy)ethanol with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 2-(2-Chloroethoxy)ethanol be handled safely?
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2-(2-Chloroethoxy)ethanol presents hazards including skin irritation (H315), serious eye damage (H318), and respiratory irritation (H335). Appropriate personal protective equipment, such as eyeshields, gloves, and suitable respirators, must be used. Handle in a well-ventilated area.
Is 2-(2-Chloroethoxy)ethanol a controlled substance?
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The provided data does not indicate that 2-(2-Chloroethoxy)ethanol is a controlled substance.
How is 2-(2-Chloroethoxy)ethanol packed and shipped?
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Tech Serve Solutions exports this chemical globally. Specific packaging and shipping details are available upon request, adhering to international regulations.
How can I request a quote or sample?
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To request a quote or sample of 2-(2-Chloroethoxy)ethanol, please contact our sales team through the website or by phone.
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