(1R,2S)-(−)-Ephedrine

CAS 299-42-3C6H5CH[CH(NHCH3)CH3]OHChemical Synthesis

(1R,2S)-(−)-Ephedrine (CAS: 299-42-3) is a naturally occurring alkaloid with a molar mass of 165.23 g/mol. Supplied with an assay of 98%, it serves as a versatile chiral synthon. Its primary applications lie in asymmetric synthesis, catalysis, and the preparation of optically pure compounds like sulfoxides and oxazolidines. Tech Serve Solutions provides this chemical for research and development purposes.

IUPAC: (−)-Ephedrine,(1R,2S)-(−)-α-(1-Methylaminoethyl)benzyl alcohol,(1R,2S)-(−)-2-Methylamino-1-phenyl-1-propanol,L-α-(1-Methylaminoethyl)benzyl alcohol
Synonyms: (−)-EphedrineC6H5CH[CH(NHCH3)CH3]OH(1R,2S)-(−)-α-(1-Methylaminoethyl)benzyl alcohol(1R,2S)-(−)-2-Methylamino-1-phenyl-1-propanolL-α-(1-Methylaminoethyl)benzyl alcohol

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(1R,2S)-(−)-Ephedrine (C6H5CH[CH(NHCH3)CH3]OH) — chemical structure, CAS 299-42-3; Chemistry, fine chemical supplied by Tech Serve Solutions

AlkaloidAsymmetric SynthesisCell BiologyChemical SynthesisChiral AuxiliariesChiral Resolution ReagentsChiral Resolving ReagentsEphedra sinicaEphedrine DerivativesNutrition Research

01 /Applications

Chiral Synthon in Asymmetric Synthesis

This compound is a valuable chiral building block used in asymmetric synthesis. It facilitates the stereoselective creation of complex molecules, particularly in the synthesis of optically pure sulfoxides and oxazolidines.

Catalysis Applications

The chiral nature of (1R,2S)-(−)-Ephedrine makes it useful in various catalytic processes. It can be employed to induce enantioselectivity in chemical reactions, a critical aspect of modern organic synthesis.

Preparation of Optically Pure Compounds

It is instrumental in the preparation of specific enantiomerically pure compounds. This includes the synthesis of sulfoxides and oxazolidines, where maintaining stereochemical integrity is crucial.

02 /Properties

Molecular weight	165.23
Linear formula	C6H5CH[CH(NHCH3)CH3]OH
Assay	98%
Boiling point	255 °C(lit.)
Density	1.124 g/mL at 25 °C(lit.)
Optical activity	[α]21/D −41°, c = 5 in 1 M HCl
Storage temperature	2-8°C
Melting point	37-39 °C(lit.)
Application	Versatile chiral synthon,1 employed in catalysis2 and in the preparation of optically pure sulfoxides3 and oxazolidines.4

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Flash point	86 °C / 186.8 °F
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	22
Safety statements (S)	22-25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

299-42-3

MDL number

MFCD00064257

PubChem substance

24848190

Beilstein registry

2208730

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1R,2S)-(−)-Ephedrine used for?

(1R,2S)-(−)-Ephedrine is used as a versatile chiral synthon in asymmetric synthesis, in catalysis, and for the preparation of optically pure sulfoxides and oxazolidines.

What is the CAS number and chemical formula for (1R,2S)-(−)-Ephedrine?

The CAS number for (1R,2S)-(−)-Ephedrine is 299-42-3. Its linear chemical formula is C6H5CH[CH(NHCH3)CH3]OH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (1R,2S)-(−)-Ephedrine with an assay of 98%. We do not claim USP, BP, or EP grades unless explicitly stated in the product data.

What are the primary safety considerations when handling (1R,2S)-(−)-Ephedrine?

Handle (1R,2S)-(−)-Ephedrine with care. It is classified under GHS07 with a warning signal word and carries the hazard statement H302 (Harmful if swallowed). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves.

How is (1R,2S)-(−)-Ephedrine packed, shipped, and exported?

Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific packing, shipping, and export details for (1R,2S)-(−)-Ephedrine are available upon request, adhering to all relevant regulations.