(1R,2S)-(−)-2-Amino-1,2-diphenylethanol
(1R,2S)-(−)-2-Amino-1,2-diphenylethanol (CAS: 23190-16-1) is a chiral amino alcohol with a molecular weight of 213.28 g/mol. This compound is a valuable chiral building block and auxiliary, primarily employed in asymmetric synthesis. Its specific stereochemistry makes it instrumental in directing stereoselective transformations, particularly in palladium-catalysed reactions for creating complex organic molecules.
- Synonyms
- 23190-16-1C6H5CH(NH2)CH(C6H5)OH
Chiral Auxiliary in Asymmetric Synthesis
This compound serves as a crucial chiral auxiliary in asymmetric synthesis. It is employed to control the stereochemical outcome of various organic reactions, leading to the formation of enantiomerically enriched products.
Palladium-Catalysed Reactions
It functions as a chiral auxiliary in Pd(II)-assisted chiral tandem alkylation and carbonylative coupling reactions. These reactions are vital for the synthesis of complex chiral molecules with high stereoselectivity.
Organic Building Block
As an organic building block, (1R,2S)-(−)-2-Amino-1,2-diphenylethanol provides a readily available source of chirality for constructing intricate molecular architectures in multi-step syntheses.
| Molecular weight | 213.28 |
|---|---|
| Linear formula | C6H5CH(NH2)CH(C6H5)OH |
| Assay | 99% |
| Optical activity | [α]25/D −7.0°, c = 0.6 in ethanol |
| Application | Chiral auxiliary used for Pd(II)-assisted chiral tandem alkylation and carbonylative coupling reactions.1,2 |
| Melting point | 142-144 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2S)-(−)-2-Amino-1,2-diphenylethanol used for?
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(1R,2S)-(−)-2-Amino-1,2-diphenylethanol is used as a chiral auxiliary, particularly in palladium-catalysed reactions such as tandem alkylation and carbonylative coupling, to promote asymmetric synthesis and create enantiomerically enriched products.
What are the CAS number and formula for this compound?
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The CAS number is 23190-16-1 and the linear formula is C14H15NO, representing C6H5CH(NH2)CH(C6H5)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2S)-(−)-2-Amino-1,2-diphenylethanol with an assay of 99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should (1R,2S)-(−)-2-Amino-1,2-diphenylethanol be handled safely?
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This compound is a Warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation and inhalation.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can export (1R,2S)-(−)-2-Amino-1,2-diphenylethanol worldwide.
How can I request a quote or sample?
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To request a quote or a sample of (1R,2S)-(−)-2-Amino-1,2-diphenylethanol, please contact our sales team through the website or by phone, providing your specific requirements.
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