(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol
(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol (CAS: 115651-77-9) is a chiral amine with a molecular weight of 263.42 g/mol. This compound, an ephedrine derivative, serves as a valuable chiral auxiliary in asymmetric synthesis. Its specific stereochemistry is crucial for directing the stereochemical outcome of various chemical reactions, making it a key reagent for producing enantiomerically pure compounds.
- IUPAC
- (+)-DBNE,N,N-Dibutyl-L-(+)-norephedrine
- Synonyms
- (+)-DBNE,N,N-Dibutyl-L-(+)-norephedrine
![(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol ([CH3(CH2)3]2NCH(CH3)CH(C6H5)OH) — chemical structure, CAS 115651-77-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F115651-77-9.png&w=3840&q=75)
Chiral Auxiliary in Asymmetric Synthesis
This compound functions as a chiral auxiliary, enabling chemists to control the stereoselectivity of reactions. It can be temporarily incorporated into a molecule to direct the formation of a new chiral center, and then subsequently removed.
Synthesis of Enantiomerically Pure Compounds
Its utility lies in the preparation of specific enantiomers of target molecules, which is critical in the pharmaceutical and fine chemical industries where stereochemistry dictates biological activity.
Reagent in Organocatalysis
As an amino alcohol, it can participate in or facilitate various organocatalytic transformations, contributing to sustainable and efficient chemical synthesis.
| Molecular weight | 263.42 |
|---|---|
| Linear formula | [CH3(CH2)3]2NCH(CH3)CH(C6H5)OH |
| Assay | 97% |
| Boiling point | 121 °C/0.1 mmHg(lit.) |
| Density | 0.94 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.501(lit.) |
| Optical activity | [α]20/D +21°, c = 2 in chloroform |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol used for?
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(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol is primarily used as a chiral auxiliary in asymmetric synthesis to produce enantiomerically pure compounds.
What are the CAS number and formula for this chemical?
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The CAS number is 115651-77-9. The linear formula is [CH3(CH2)3]2NCH(CH3)CH(C6H5)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should this chemical be handled safely?
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This compound is a Warning-level irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and avoid breathing dust/fume/gas/mist/vapours/spray.
Is this product available for export and how is it shipped?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. Shipping and packaging adhere to international regulations for chemical transport.
How can I request a sample or quote?
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Please contact our sales team via the website or directly via email/phone to request a sample or a quotation for this product.
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