4,4,4,4′,4′,4′-Hexafluoro-DL-valine
4,4,4,4′,4′,4′-Hexafluoro-DL-valine (CAS: 16063-80-2), with the linear formula (CF₃)₂CHCH(NH₂)COOH and a molecular weight of 225.09 g/mol, is a fluorinated amino acid derivative. This compound finds utility as a building block in chemical synthesis, particularly within peptide chemistry and the development of unnatural amino acids for chemical biology research. Its unique fluorinated structure offers distinct properties for advanced molecular design.
- IUPAC
- 2-Amino-4,4,4-trifluoro-3-(trifluoromethyl)butyric acid,4,4,4,5,5,5-Hexafluoro-DL-valine
- Synonyms
- 4′,4′,4′-Hexafluoro-DL-valine2-Amino-4,4,4-trifluoro-3-(trifluoromethyl)butyric acid4,4,4,5,5,5-Hexafluoro-DL-valine
Chemical Synthesis Building Block
Utilised as a specialised synthon for introducing fluorinated motifs into organic molecules. Its structure makes it valuable for constructing complex target compounds in multi-step syntheses.
Peptide Chemistry Research
Incorporated into peptide chains to create fluorinated analogues with altered physicochemical properties. This can influence peptide conformation, stability, and biological activity.
Chemical Biology Tool
Serves as a component in the design of novel biomolecules and probes. The trifluoromethyl groups can enhance metabolic stability or modulate binding interactions.
Unnatural Amino Acid Derivative
Employed in the study and synthesis of non-proteinogenic amino acids, expanding the toolkit for medicinal chemistry and drug discovery efforts.
| Molecular weight | 225.09 |
|---|---|
| Linear formula | (CF3)2CHCH(NH2)COOH |
| Assay | 97% |
| Melting point | 196-217 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4,4,4′,4′,4′-Hexafluoro-DL-valine used for?
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4,4,4,4′,4′,4′-Hexafluoro-DL-valine is primarily used as a building block in chemical synthesis, peptide chemistry, and chemical biology research for creating fluorinated analogues and unnatural amino acid derivatives.
What are the CAS number and formula for 4,4,4,4′,4′,4′-Hexafluoro-DL-valine?
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The CAS number is 16063-80-2, and the linear formula is (CF₃)₂CHCH(NH₂)COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4,4,4′,4′,4′-Hexafluoro-DL-valine with an assay of 97%. This product is intended for research and synthesis purposes and is not supplied as USP, BP, or EP grade.
What are the safety considerations for handling 4,4,4,4′,4′,4′-Hexafluoro-DL-valine?
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This compound is classified under WGK 3 (Germany). Appropriate personal protective equipment should be worn, and handling should occur in a well-ventilated area or fume hood to avoid inhalation and skin contact. Consult the Safety Data Sheet (SDS) for detailed hazard information.
How is 4,4,4,4′,4′,4′-Hexafluoro-DL-valine packed and shipped?
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4,4,4,4′,4′,4′-Hexafluoro-DL-valine is carefully packaged to ensure stability during transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical substances.
How can I request a sample or quote for 4,4,4,4′,4′,4′-Hexafluoro-DL-valine?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team directly. Please include the product name and CAS number (16063-80-2) in your request.
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