4,4,4-Trifluorobutyric acid
4,4,4-Trifluorobutyric acid (CAS: 406-93-9), with a molecular formula of C4H5F3O2 and a molecular weight of 142.08 g/mol, is a fluorinated carboxylic acid. It serves as a versatile building block in organic synthesis, particularly valued for introducing the trifluoropropyl group. This compound is primarily utilised in the development of new materials and pharmaceutical intermediates, owing to the unique electronic and steric properties conferred by the trifluoromethyl group.
- Synonyms
- 406-93-9C4H5F3O2
Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of complex organic molecules. Its trifluoromethyl group allows for modification of molecular properties like lipophilicity and metabolic stability, making it valuable in medicinal chemistry.
Pharmaceutical Development
A crucial component in the synthesis of novel pharmaceutical candidates. The incorporation of fluorine can enhance drug efficacy and pharmacokinetic profiles, driving innovation in drug discovery.
Materials Science
Employed in the creation of advanced materials where fluorination imparts desirable characteristics such as thermal stability and chemical resistance. This includes applications in polymers and specialty chemicals.
| Molecular weight | 142.08 |
|---|---|
| Empirical formula | C4H5F3O2 |
| Assay | 97% |
| Refractive index | n20/D 1.351 |
| Storage temperature | 2-8°C |
| Melting point | 25-31 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 96 °C / 204.8 °F |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,4,4-Trifluorobutyric acid used for?
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4,4,4-Trifluorobutyric acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and advanced materials where the trifluoromethyl group imparts specific electronic and steric properties.
What is the CAS number and formula for 4,4,4-Trifluorobutyric acid?
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The CAS number for 4,4,4-Trifluorobutyric acid is 406-93-9, and its empirical formula (Hill notation) is C4H5F3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,4,4-Trifluorobutyric acid with an assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeial grades unless explicitly stated.
How should 4,4,4-Trifluorobutyric acid be handled?
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4,4,4-Trifluorobutyric acid is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure adequate ventilation.
Is 4,4,4-Trifluorobutyric acid available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4,4,4-Trifluorobutyric acid, adhering to all necessary shipping and regulatory requirements.
How can I request a quote or sample for 4,4,4-Trifluorobutyric acid?
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To request a quote or sample of 4,4,4-Trifluorobutyric acid, please use the contact form on our website or contact our sales department directly.
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