15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid
15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid (CAS: 54845-95-3), a C20H32O3 molecule with a molecular weight of 320.47 g/mol, is a key oxylipin derived from arachidonic acid. It plays a role in cellular signalling pathways. This compound is utilised in biochemical research and studies related to cell biology and neuroscience, serving as a valuable reagent for investigating lipid metabolism and inflammatory responses.
- IUPAC
- (15S,5Z,8Z,11Z,13E)-15-Hydroxyeicosatetraenoic acid,(S)-15-HETE,15(S)-HETE
- Synonyms
- 13E)-eicosatetraenoic acid,54845-95-3, C20H32O3,(15S,5Z,8Z,11Z,13E)-15-Hydroxyeicosatetraenoic acid,(S)-15-HETE,15(S)-HETE
Biochemical Research Reagent
This hydroxyeicosatetraenoic acid serves as a critical reagent in biochemical and lipid research. Its specific stereochemistry and fatty acid structure make it valuable for studying metabolic pathways and enzyme activity.
Cell Biology Studies
Utilised in cell biology, this compound aids in investigating cellular signalling cascades and the physiological roles of oxylipins. Researchers employ it to understand cell membrane dynamics and responses to stimuli.
Neuroscience Research
As a component of the arachidonic acid cascade, 15(S)-HETE is relevant in neuroscience research. It can be used to explore its potential involvement in neurological processes and conditions.
Investigating Inflammatory Responses
This molecule is instrumental in studies focused on inflammation and immune responses. Its role as an oxylipin allows researchers to probe the mechanisms underlying inflammatory processes.
| Molecular weight | 320.47 |
|---|---|
| Empirical formula | C20H32O3 |
| Assay | ≥97.0% (HPLC) |
| Concentration | ~150 μg/mL in ethanol |
| Storage temperature | −20°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 14 °C / 57.2 °F |
| Transport (UN / ADR) | UN 1170C 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 7-16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid used for?
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This compound is primarily used as a reagent in biochemical research, cell biology studies, and neuroscience research, particularly for investigating the arachidonic acid cascade and inflammatory responses.
What are the CAS number and formula for 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid?
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The CAS number is 54845-95-3, and the empirical formula is C20H32O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97.0% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How is 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid supplied and stored?
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The product is shipped in dry ice and should be stored at -20°C to maintain its integrity. It is typically supplied at a concentration of approximately 150 μg/mL in ethanol.
What are the primary safety hazards associated with this chemical?
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This chemical is highly flammable (H225) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is classified with the signal word 'Danger'.
How can I request a sample or quote for this product?
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Please contact our sales team via the website or telephone to request a sample or a formal quotation for 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid.
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