1400W dihydrochloride

CAS 214358-33-5C10H15N3 · 2 HClBiochemicals & Reagents

1400W dihydrochloride (CAS 214358-33-5) is a bioactive small molecule with the chemical formula C10H15N3 · 2 HCl and a molecular weight of 250.17 g/mol. This compound functions as a selective inhibitor of nitric oxide synthase (NOS) isoforms. It is utilized in biochemical research, particularly for studying cell signalling pathways and the role of nitric oxide in various physiological and pathological processes.

IUPAC: N-([3-(Aminomethyl)phenyl]methyl)ethanimidamide dihydrochloride
Synonyms: N-([3-(Aminomethyl)phenyl]methyl)ethanimidamide dihydrochloride

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1400W dihydrochloride (C10H15N3 · 2 HCl) — chemical structure, CAS 214358-33-5; Life Science, fine chemical supplied by Tech Serve Solutions

Application IndexBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCell Signaling EnzymesEnzymesInhibitorsand SubstratesGlaxoSmithKlineNOS Inhibitors

01 /Applications

Nitric Oxide Synthase (NOS) Inhibition

1400W dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS), making it a valuable tool for research into the physiological and pathological roles of nitric oxide.

Cell Signalling Research

This compound aids in the investigation of cell signalling pathways regulated by nitric oxide, offering insights into processes such as inflammation, neurotransmission, and cardiovascular function.

Drug Candidate Research

As an approved therapeutic/drug candidate, it is studied for its potential in developing treatments for conditions where NOS overactivity is implicated, such as inflammatory diseases.

Biochemical and Reagent Use

Utilised as a biochemical reagent in laboratory settings for in vitro and in vivo studies requiring precise modulation of NO production.

02 /Properties

Molecular weight	250.17
Empirical formula	C10H15N3 · 2 HCl
Assay	>98%
Form	solid
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

214358-33-5

MDL number

MFCD03428622

PubChem substance

24278778

05 /Additional specifications

Shipped In	wet ice
Gene Information	human ... NOS1(4842), NOS2(4843), NOS3(4846)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 1400W dihydrochloride used for?

1400W dihydrochloride is primarily used as a selective inhibitor of nitric oxide synthase (NOS) enzymes in biochemical and cell biology research. It is instrumental in studying the roles of nitric oxide in cell signalling, inflammation, and various physiological processes, and is considered an approved therapeutic/drug candidate.

What are the CAS number and chemical formula for 1400W dihydrochloride?

The CAS number for 1400W dihydrochloride is 214358-33-5, and its chemical formula is C10H15N3 · 2 HCl.

What grade and purity does Tech Serve Solutions supply for 1400W dihydrochloride?

Tech Serve Solutions supplies 1400W dihydrochloride with an assay of >98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade; it is intended for research and laboratory use.

How is 1400W dihydrochloride stored and shipped?

1400W dihydrochloride is stored at -20°C and is shipped on wet ice to maintain its stability and integrity during transit.

What safety precautions should be taken when handling 1400W dihydrochloride?

When handling 1400W dihydrochloride, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified under WGK Germany 3, indicating a high hazard.

How can I request a sample or quote for 1400W dihydrochloride?

To request a sample or a quote for 1400W dihydrochloride, please contact our sales team through the website or by phone. Details for sample and quote requests are available in the 'Contact Us' section.