16,16-Dimethylprostaglandin E2
16,16-Dimethylprostaglandin E2 (CAS: 39746-25-3) is a synthetic analogue of the naturally occurring prostaglandin E2. With a molecular weight of 380.52 g/mol and empirical formula C22H36O5, this compound is supplied as a methyl acetate solution. It serves as a valuable biochemical reagent, particularly in research related to cell biology and stem cell applications, owing to its role in mediating various physiological processes.
- Synonyms
- 16,16-Dimethylprostaglandin E2(5Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E,3S)-3-hydroxy-3-methyl-1-octen-6-yn-1-yl)cyclopentyl)-5-heptenoic acid methyl ester

Biochemical Research
Utilised as a research tool in cell biology and stem cell studies to investigate cellular signalling pathways and developmental processes. Its structural similarity to endogenous prostaglandins makes it useful for understanding receptor interactions and downstream effects.
Eicosanoid Studies
Serves as a model compound for studying the metabolism and biological activity of eicosanoids, specifically prostaglandins. Researchers use it to explore inflammation, pain, and other physiological responses regulated by these lipid mediators.
Drug Discovery and Development
Investigated in early-stage drug discovery programmes targeting prostaglandin pathways. Its synthetic nature allows for controlled experimental conditions in preclinical research.
| Molecular weight | 380.52 |
|---|---|
| Empirical formula | C22H36O5 |
| Form | methyl acetate solution |
| Concentration | ~10 mg/mL |
| Storage temperature | −20°C |

Hazard statements
- H319Causes serious eye irritation
- H336May cause drowsiness or dizziness
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 1231 3 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36-66-67 |
| Safety statements (S) | 26 |
| Supplemental hazards | Repeated exposure may cause skin dryness or cracking. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | wet ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 16,16-Dimethylprostaglandin E2 used for?
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16,16-Dimethylprostaglandin E2 is primarily used in biochemical and cell biology research, particularly in stem cell studies and investigations into eicosanoid pathways. It serves as a research tool to understand cellular signalling and physiological processes.
What are the CAS number and formula for 16,16-Dimethylprostaglandin E2?
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The CAS number for 16,16-Dimethylprostaglandin E2 is 39746-25-3, and its empirical formula is C22H36O5.
What grade and purity does Tech Serve Solutions supply for 16,16-Dimethylprostaglandin E2?
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Tech Serve Solutions supplies 16,16-Dimethylprostaglandin E2 as a methyl acetate solution at a concentration of approximately 10 mg/mL. TSS does not represent this product as USP, BP, or EP grade; it is intended for research purposes.
How is 16,16-Dimethylprostaglandin E2 handled and stored?
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16,16-Dimethylprostaglandin E2 is supplied as a methyl acetate solution and is classified as a Warning. It can cause serious eye irritation (H319) and may cause drowsiness or dizziness (H336). Repeated exposure may cause skin dryness or cracking. Appropriate personal protective equipment, including eyeshields and gloves, should be used. It is stored at -20°C.
How is 16,16-Dimethylprostaglandin E2 shipped?
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16,16-Dimethylprostaglandin E2 is shipped in wet ice to maintain its stability during transit.
How can I request a quote or sample for 16,16-Dimethylprostaglandin E2?
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To request a quote or sample for 16,16-Dimethylprostaglandin E2, please contact our sales department through the TSS website or by phone.
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