Diethylphosphine
Diethylphosphine (CAS: 627-49-6, C4H11P) is an organophosphorus compound with a molecular weight of 90.10 g/mol. This flammable liquid is a pyrophoric substance, igniting spontaneously in air, and is corrosive. It finds primary utility as a ligand in coordination chemistry and catalysis, and as a building block in the synthesis of more complex organophosphorus compounds.

Ligand in Catalysis
Diethylphosphine serves as a ligand in homogeneous catalysis, coordinating with transition metals to influence reaction selectivity and activity in processes such as cross-coupling reactions.
Chemical Synthesis Intermediate
It acts as a precursor or intermediate in the synthesis of various organophosphorus compounds, including phosphine oxides and phosphonium salts, which have applications in diverse chemical fields.
Reagent in Organophosphorus Chemistry
As a reactive organophosphorus compound, it is employed in research and development for the creation of novel phosphorus-containing molecules and materials.
| Molecular weight | 90.10 |
|---|---|
| Empirical formula | C4H11P |
| Assay | 98% |
| Density | 0.782 g/mL at 25 °C |



Hazard statements
- H250Catches fire spontaneously if exposed to air
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P222Do not allow contact with air
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
- P422
| Transport (UN / ADR) | UN 2845 4.2 |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 17-20/21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethylphosphine used for?
+
Diethylphosphine is primarily used as a ligand in catalysis and as an intermediate in the synthesis of organophosphorus compounds.
What is the CAS number and formula for Diethylphosphine?
+
The CAS number is 627-49-6 and the molecular formula is C4H11P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Diethylphosphine with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should Diethylphosphine be handled safely?
+
Diethylphosphine is pyrophoric and ignites spontaneously in air (H250), is harmful if swallowed (H302), in contact with skin (H332), and if inhaled (H332), and causes severe skin burns and eye damage (H314). It must be handled under an inert atmosphere, with appropriate personal protective equipment, and away from ignition sources.
How is Diethylphosphine packed, shipped, and exported?
+
Diethylphosphine is shipped as a hazardous material, classified under UN 2845, Class 4.2. Specific packaging and export regulations apply to ensure safe transport, and TSS adheres to all relevant international shipping standards.
How can I request a sample or quote for Diethylphosphine?
+
To request a sample or quote, please contact our sales team via the website or direct phone line, providing your specific requirements.
▶ Related products

Benzeneruthenium(II) chloride dimer
Ru2(C6H6)2Cl4
Catalysis & Inorganic
Benzoylferrocene
C17H14FeO
Catalysis & Inorganic
Benzyldiphenylphosphine
C6H5CH2P(C6H5)2
Catalysis & Inorganic
Beryllium
Be
Catalysis & Inorganic
Beryllium oxide
BeO
Catalysis & Inorganic![Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer — chemical structure, CAS 12257-42-0; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F12257-42-0.png&w=3840&q=75)
Bicyclo[2.2.1]hepta-2,5-diene-rhodium(I) chloride dimer
Catalysis & Inorganic
![Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo — chemical structure, CAS 1228149-03-8; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1228149-03-8.png&w=3840&q=75)
Bis[(10,11-η)-5-[(11bS)-dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl- κP4]-5H-dibenz[b,f]azepine]rhodium(I) tetrafluorobo
1-d:1′
Catalysis & Inorganic![Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride (C16H20ClN3Ni) — chemical structure, CAS 1033772-47-2; Catalysis & Inorganic, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1033772-47-2.png&w=3840&q=75)
Bis[(2-dimethylamino)phenyl]amine nickel(II) chloride
C16H20ClN3Ni
Catalysis & Inorganic


