Cyclohexylboronic acid
Cyclohexylboronic acid (CAS: 4441-56-9), with the molecular formula C6H13BO2 and a molecular weight of 127.98 g/mol, is an organoboron compound. It serves as a versatile building block in organic synthesis. Its applications include participation in various cross-coupling reactions and as a reactant in the synthesis of specific organic compounds.

Suzuki Cross-Coupling Reactions
Cyclohexylboronic acid is a key reagent in Suzuki cross-coupling reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides.
HF-Free Synthesis
This compound is utilised as a reactant in the HF-free synthesis of tetrabutylammonium trifluoroborates, a process important for generating specific ionic compounds.
Cross-Coupling with Amines
It participates in cross-coupling reactions with aromatic amines, facilitating the synthesis of substituted aniline derivatives.
Arylation and Alkylation
Cyclohexylboronic acid is employed in the arylation and alkylation of diphenylisoxazole, contributing to the synthesis of complex heterocyclic structures.
| Molecular weight | 127.98 |
|---|---|
| Empirical formula | C6H13BO2 |
| Application | Reactant involved in:• HF-free synthesis of tetrabutylammonium trifluoroborates1• Cross-coupling with aromatic amines2• Suzuki cross-coupling reactions3• Arylation and alkylation of diphenylisoxazole4 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclohexylboronic acid used for?
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Cyclohexylboronic acid is used as a reactant in organic synthesis, particularly in Suzuki cross-coupling reactions, HF-free synthesis of tetrabutylammonium trifluoroborates, and the arylation/alkylation of diphenylisoxazole.
What is the CAS number and formula for Cyclohexylboronic acid?
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The CAS number is 4441-56-9, and the molecular formula is C6H13BO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are available upon request. We do not represent this product as USP, BP, EP, or for nutraceutical, food, or medicinal use.
What are the safety considerations when handling Cyclohexylboronic acid?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if necessary, as indicated by the safety data sheet.
How is Cyclohexylboronic acid packed, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions ensures that all chemicals are packed, handled, and shipped in compliance with international regulations for fine chemicals and laboratory reagents.
How can I request a sample or quote for Cyclohexylboronic acid?
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You can request a sample or a quote by contacting our sales team through the website or by calling our dedicated customer service line.
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