α-Zearalenol
α-Zearalenol (CAS 36455-72-8), a resorcylic acid lactone with the empirical formula C18H24O5 and molecular weight 320.38, is a naturally occurring mycotoxin with estrogenic activity. It is a metabolite of zearalenone and is primarily utilised in research settings for studies involving cell biology, endocrine disruption, and hormone receptor interactions. Its specific chemical structure and biological effects make it a valuable tool for scientific investigation.
- IUPAC
- 2,4-Dihydroxy-6-(6α,10-dihydroxy-trans-1-undecenyl)benzoic acid μ-lactone
Endocrine Disruption Research
Investigating the estrogenic effects and potential endocrine-disrupting properties of mycotoxins in biological systems. This compound serves as a model for studying interactions with estrogen receptors.
Cell Biology Studies
Utilised in cell culture experiments to examine the impact of xenoestrogens on cellular processes, proliferation, and signalling pathways. It aids in understanding cellular responses to hormonal stimuli.
Biochemical Assays
Employed as a standard or reference compound in biochemical assays designed to detect or quantify related estrogenic substances or to study enzyme activity involved in steroid metabolism.
Hormone Receptor Modulation
Used to probe the binding affinity and functional activity of estrogen receptors, contributing to a deeper understanding of hormone-dependent gene expression and cellular responses.
| Molecular weight | 320.38 |
|---|---|
| Empirical formula | C18H24O5 |
| Storage temperature | −20°C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H336May cause drowsiness or dizziness
- H340May cause genetic defects
- H350May cause cancer
- H361FD
- H371May cause damage to organs
- H373May cause damage to organs through prolonged exposure
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P201Obtain special instructions before use
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P273Avoid release to the environment
- P281Use personal protective equipment as required
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-20/21/22-48/20/22-52/53-62-68/20/21/22 |
| Safety statements (S) | 53-36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Ar(24208) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Zearalenol used for?
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α-Zearalenol is primarily used in research for studying endocrine disruption, cell biology, biochemical assays involving hormone receptors, and investigating its estrogenic effects.
What is the CAS number and formula for α-Zearalenol?
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The CAS number for α-Zearalenol is 36455-72-8, and its empirical formula is C18H24O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies α-Zearalenol for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as meeting USP, BP, or EP standards.
What are the main hazards associated with α-Zearalenol?
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α-Zearalenol is classified with a 'Danger' signal word and carries significant hazards including potential genetic defects, cancer, damage to fertility or the unborn child, and organ damage. It is also harmful if swallowed, causes skin and serious eye irritation, and may cause drowsiness or dizziness. It is also toxic to aquatic life with long lasting effects. Always consult the Safety Data Sheet (SDS) before handling.
How is α-Zearalenol packed and shipped?
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α-Zearalenol is typically stored at -20°C. For export, it is packaged securely in compliance with all relevant shipping regulations to ensure product integrity and safety during transit.
How can I request a sample or quote for α-Zearalenol?
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To request a sample or a quote for α-Zearalenol, please contact our sales team through the TSS website or by calling our office, providing the product name and CAS number.
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