α-Naphtholbenzein
α-Naphtholbenzein (CAS: 145-50-6) is a chemical compound with the formula C27H18O2 and a molecular weight of 374.43 g/mol. It serves as a vital indicator in analytical chemistry, particularly for non-aqueous titrations, where its distinct colour change signifies the endpoint. This reagent is essential for precise chemical analysis in various laboratory settings, supporting accurate determination of substance concentrations.
- IUPAC
- 4,4′-(α-Hydroxybenzylidene)di-1-naphthol,p-naphtholbenzein
- Synonyms
- 4,4′-(α-Hydroxybenzylidene)di-1-naphtholp-naphtholbenzein

pH Indicator
α-Naphtholbenzein functions as a pH indicator, exhibiting a colour transition within the pH range of 8.2 to 10.0. This property makes it useful for monitoring acid-base reactions in aqueous and non-aqueous systems.
Non-Aqueous Titration Reagent
This compound is specifically employed as an indicator for non-aqueous titrations. It allows for accurate determination of endpoints in titrations conducted in organic solvents where traditional aqueous indicators may not be suitable.
Analytical Chemistry
As a key analytical reagent, α-Naphtholbenzein supports various chemical analyses. Its application in microscopy and histology, along with its use in cell biology, highlights its versatility in scientific research and diagnostics.
| Molecular weight | 374.43 |
|---|---|
| Empirical formula | C27H18O2 |
| Grade | indicator (pH 8.2-10.0) |
| Melting point | 230-235 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Naphtholbenzein used for?
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α-Naphtholbenzein is primarily used as a pH indicator, particularly for non-aqueous titrations, and in analytical chemistry procedures such as microscopy, histology, and cell biology.
What are the CAS number and chemical formula for α-Naphtholbenzein?
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The CAS number for α-Naphtholbenzein is 145-50-6, and its chemical formula is C27H18O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies α-Naphtholbenzein as an indicator (pH 8.2-10.0). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should α-Naphtholbenzein be handled safely?
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Handle α-Naphtholbenzein with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is α-Naphtholbenzein shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including α-Naphtholbenzein, and can arrange for international shipping.
How can I request a sample or quote for α-Naphtholbenzein?
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To request a sample or a quotation for α-Naphtholbenzein, please contact our sales department through the website or by telephone.
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