α5IA

CAS 215874-86-5C17H14N8O2Cell Biology

Alpha-5-IA (CAS: 215874-86-5), with the molecular formula C17H14N8O2 and a molecular weight of 362.35 g/mol, is an off-white to light yellow powder. This compound serves as a selective agonist for GABA-A receptors and is utilised in neurochemical research. Its applications primarily lie within cell biology and neuroscience, aiding investigations into neurotransmission and cell signaling pathways.

IUPAC: 1,2,4-Triazolo[3,4-a]phthalazine, 3-(5-methyl-3-isoxazolyl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy]-,3-(5-Methylisoxazol-3-yl)-6-(1-methyl-1,2,3-triazol-4-yl)methoxy-1,2,4-triazolo[3,4-a]phthalazine
Synonyms: 3-(5-Methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy]-1,2,4-triazolo[3,4-a]phthalazine3-(5-Methylisoxazol-3-yl)-6-(1-methyl-1,2,3-triazol-4-yl)methoxy-1,2,4-triazolo[3,4-a]phthalazine

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α5IA (C17H14N8O2) — chemical structure, CAS 215874-86-5; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Neuroscience Research

Alpha-5-IA is employed as a research tool to study the role of the alpha-5 subunit-containing GABA-A receptors in various neurological processes. It helps elucidate mechanisms of neurotransmission and synaptic plasticity.

Cell Signaling Studies

This compound can be used in cell biology to investigate signaling cascades modulated by GABAergic neurotransmission. It aids in understanding cellular responses related to neuronal communication.

Drug Discovery and Development

As an approved therapeutic candidate or drug candidate, Alpha-5-IA's properties are explored in preclinical research for potential therapeutic applications related to neurological disorders.

02 /Properties

Molecular weight	362.35
Empirical formula	C17H14N8O2
Assay	≥98% (HPLC)
Form	powder
Colour	off-white to light yellow
Solubility	DMSO: >2 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

215874-86-5

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Alpha-5-IA used for?

Alpha-5-IA is primarily used in neuroscience research for studying GABA-A receptors, particularly those containing the alpha-5 subunit, and their role in neurotransmission and cell signaling.

What are the CAS number and molecular formula for Alpha-5-IA?

The CAS number for Alpha-5-IA is 215874-86-5, and its molecular formula is C17H14N8O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Alpha-5-IA with a purity of ≥98% (HPLC). This is a research-grade chemical and is not represented as USP, BP, or EP.

How should Alpha-5-IA be handled safely?

When handling Alpha-5-IA, use appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating it is hazardous.