Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride

CAS 65147-22-0C33H36N6O6 · HClBiochemicals & Reagents

Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride (CAS 65147-22-0), with molecular formula C33H36N6O6 · HCl and molecular weight 649.14, is a fluorogenic peptide substrate. It is primarily utilised in biochemical research for studying enzyme activity, particularly proteases. Its specific structure allows for sensitive detection of enzyme cleavage, making it valuable in cell biology and signalling pathway investigations.

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Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride (C33H36N6O6 · HCl) — chemical structure, CAS 65147-22-0; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsCell BiologyEnzyme SubstratesEnzymesInhibitorsand SubstratesKallikreinPeptides and ProteinsPeptides for Cell BiologyProtease Substrates

01 /Applications

Enzyme Activity Assays

This compound serves as a sensitive fluorogenic substrate for the characterisation and quantification of protease activity. Upon enzymatic cleavage, it releases a fluorescent product, enabling real-time monitoring of enzyme kinetics.

Biochemical Research

It is widely applied in biochemical and cell biology research to investigate enzyme function, substrate specificity, and the regulation of biological processes involving proteases.

Cell Signaling Studies

Used in studies related to cell signaling pathways where specific proteases play a crucial role. Its cleavage can be correlated with cellular events and pathway activation.

Neuroscience Research

Applicable in neuroscience for the study of enzymes involved in neural processes and the characterisation of their substrates.

02 /Properties

Molecular weight	649.14
Empirical formula	C33H36N6O6 · HCl
Concentration	≥95%
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

65147-22-0

MDL number

MFCD00077030

PubChem substance

24893165

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride used for?

Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride is primarily used as a fluorogenic substrate in biochemical research for studying protease activity, enzyme kinetics, and cell signaling pathways.

What are the CAS number and molecular formula for this product?

The CAS number is 65147-22-0 and the molecular formula is C33H36N6O6 · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with a purity of ≥95%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmaceutical grade.

How should Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride be handled?

Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Observe safety precautions appropriate for laboratory chemicals. The WGK Germany is 3.

How is this product shipped?

This product is typically shipped under refrigeration. As a global supplier and exporter, Tech Serve Solutions ensures compliant packaging and documentation for international shipments.

How can I request a sample or quote?

To request a sample or a quote, please contact our sales department through the website or by calling us directly. Our team will assist you with your requirements.