Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride
Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride (CAS: 102601-58-1) is a fluorogenic peptide substrate with the molecular formula C28H33N7O7 · HCl and a molecular weight of 616.07 g/mol. This compound is designed for the detection and quantification of protease activity. It is primarily utilised in biochemical research, particularly in studies involving cell signalling, neuroscience, and coagulation processes, where accurate measurement of enzymatic activity is critical for understanding biological mechanisms.
Protease Activity Assays
This fluorogenic substrate is employed to detect and measure the activity of specific proteases. Upon enzymatic cleavage, it releases a fluorescent aminocoumarin moiety, allowing for sensitive detection of enzyme kinetics and inhibition.
Biochemical Research
Used as a tool in various biochemical investigations, including studies of cell signalling pathways and neurological processes. Its application aids in elucidating the role of proteases in biological functions.
Coagulation Studies
This substrate finds application in research related to the coagulation cascade. It can be used to investigate the activity of proteases involved in blood clotting mechanisms.
Drug Discovery and Development
Serves as a valuable reagent in screening for protease inhibitors, which are important targets in therapeutic development. Its use facilitates the identification of potential drug candidates that modulate protease activity.
| Molecular weight | 616.07 |
|---|---|
| Empirical formula | C28H33N7O7 · HCl |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride used for?
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It is used as a fluorogenic substrate for the detection and quantification of protease activity in biochemical research, cell signalling studies, neuroscience, and coagulation research.
What is the CAS number and formula for Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride?
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The CAS number is 102601-58-1 and the formula is C28H33N7O7 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research grade chemical. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating it is hazardous to water.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is stored at -20°C and shipped according to appropriate regulations for chemical transport.
How can I request a sample or quote for this chemical?
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Please contact our sales team via the website or direct inquiry to request a sample or obtain a quotation for Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride.
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