Z-Gln-ONp
Z-Gln-ONp (CAS: 7763-16-8) is a protected amino acid derivative with the linear formula NH<sub>2</sub>COCH<sub>2</sub>CH<sub>2</sub>CH(NHCOOCH<sub>2</sub>C<sub>6</sub>H<sub>5</sub>)COOC<sub>6</sub>H<sub>4</sub>NO<sub>2</sub> and a molecular weight of 401.37 g/mol. This compound is a key reagent in peptide synthesis, facilitating the formation of peptide bonds. It is primarily utilised in research and development within the biochemical and pharmaceutical sectors for the creation of custom peptides and complex biomolecules.
- IUPAC
- N-α-Cbz-L-glutamine p-nitrophenyl ester,Z-L-glutamine 4-nitrophenyl ester
- Synonyms
- N-α-Cbz-L-glutamine p-nitrophenyl esterZ-L-glutamine 4-nitrophenyl ester

Peptide Synthesis
Z-Gln-ONp serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis. Its p-nitrophenyl ester leaving group activates the carboxyl function for efficient coupling reactions, enabling the formation of peptide bonds.
Biochemical Research
It is employed in research laboratories for synthesising peptides with specific sequences and modifications. This is crucial for studying peptide structure-activity relationships and developing novel therapeutic peptides.
Modified Amino Acid Synthesis
As a modified amino acid, Z-Gln-ONp can be incorporated into synthetic peptides to introduce specific chemical properties or functionalities, aiding in the development of peptidomimetics and functional biomaterials.
| Molecular weight | 401.37 |
|---|---|
| Linear formula | NH2COCH2CH2CH(NHCOOCH2C6H5)COOC6H4NO2 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Gln-ONp used for?
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Z-Gln-ONp is primarily used as a protected amino acid derivative in peptide synthesis and biochemical research for constructing specific peptide sequences and modified biomolecules.
What are the CAS number and formula for Z-Gln-ONp?
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The CAS number for Z-Gln-ONp is 7763-16-8. Its linear formula is NH₂COCH₂CH₂CH(NHCOOCH₂C₆H₅)COOC₆H₄NO₂.
What grade and purity does Tech Serve Solutions supply for Z-Gln-ONp?
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Tech Serve Solutions supplies Z-Gln-ONp for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis, and it is not represented as USP, BP, or EP grade.
How should Z-Gln-ONp be handled and stored?
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Handle Z-Gln-ONp with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter may be necessary. It should be stored at -20°C.
Is Z-Gln-ONp a controlled substance?
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The provided data does not indicate that Z-Gln-ONp is a controlled substance.
How is Z-Gln-ONp packed and shipped?
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Z-Gln-ONp is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for Z-Gln-ONp?
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To request a sample or a quote for Z-Gln-ONp, please contact the Tech Serve Solutions sales team through the website or by calling our customer service number.
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