Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride
Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride (CAS: 63424-41-9; Formula: C29H35N7O6 · HCl; MW: 614.09) is a synthetic peptide derivative primarily utilised as a chromogenic substrate. It is instrumental in the quantitative determination of enzyme activity, particularly urokinase, due to its ability to release a coloured product upon enzymatic cleavage. This compound is a valuable reagent in biochemical research, cell biology studies, and investigations into coagulation and related enzymatic pathways.
Chromogenic Substrate for Enzyme Assays
This compound serves as a chromogenic substrate for quantifying enzyme activity. Upon enzymatic hydrolysis by specific proteases, such as urokinase, it releases 4-methoxy-β-naphthylamine, which can be measured spectrophotometrically.
Biochemical Research
It is employed in fundamental biochemical research to study enzyme kinetics and mechanisms. Its use helps elucidate the roles of proteases in various biological processes and pathways.
Cell Biology Studies
Used in cell biology to investigate cellular processes involving proteolytic enzymes, including cell signalling and extracellular matrix remodelling. It aids in understanding enzyme function within cellular environments.
Coagulation Research
This substrate is relevant in research related to the coagulation cascade and fibrinolysis. Its application can help in the study of enzymes involved in blood clotting and clot dissolution.
| Molecular weight | 614.09 |
|---|---|
| Empirical formula | C29H35N7O6 · HCl |
| Storage temperature | −20°C |
Hazard statements
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride used for?
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Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride is primarily used as a chromogenic substrate for enzyme assays, particularly for quantifying the activity of urokinase and other related proteases.
What are the CAS number and molecular formula for Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride?
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The CAS number is 63424-41-9, and the molecular formula is C29H35N7O6 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research purposes. The specific assay and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride be handled?
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This compound is classified under GHS08 with a 'Warning' signal word and the hazard statement H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N100 or P3 filters), must be used. Handle in a well-ventilated area and follow standard laboratory safety protocols.
How is this chemical packed, shipped, and exported?
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This product is typically stored at -20°C. TSS ensures secure and compliant packaging for domestic and international shipments, adhering to all relevant shipping regulations for chemical export.
How can I request a sample or obtain a quote?
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To request a sample or a quotation for Z-Gly-Gly-Arg 4-methoxy-β-naphthylamide hydrochloride, please contact our sales department via the website or by phone.
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