Z-D-Prolinol
Z-D-Prolinol (CAS 72597-18-3, C13H17NO3) is a versatile chiral amino alcohol with a molecular weight of 235.28 g/mol. It is primarily utilised in advanced chemical synthesis and peptide chemistry, serving as a valuable building block for complex organic molecules. This compound is essential for researchers and manufacturers requiring high-purity reagents for stereoselective synthesis and the development of novel chemical entities.
- IUPAC
- (R)-2-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester

Chiral Synthesis
Z-D-Prolinol acts as a chiral auxiliary or building block in asymmetric synthesis, enabling the stereoselective preparation of complex organic molecules with defined chirality. Its structure facilitates enantioselective transformations critical in pharmaceutical and fine chemical production.
Peptide Chemistry
This compound is employed in peptide synthesis, particularly for incorporating modified amino acid residues or as a precursor for peptidomimetics. It aids in the construction of peptide-based drugs and research tools.
Chemical Biology Research
Z-D-Prolinol finds application in chemical biology for the synthesis of probes and labelled molecules. It assists in studying biological processes at the molecular level and developing new diagnostic or therapeutic agents.
Pharmaceutical Intermediate
As a key intermediate, Z-D-Prolinol is integral to the multi-step synthesis of active pharmaceutical ingredients (APIs). Its chiral nature is often essential for the biological activity of the final drug product.
| Molecular weight | 235.28 |
|---|---|
| Empirical formula | C13H17NO3 |
| Assay | 97% |
| Density | 1.135 g/mL at 25 °C |
| Refractive index | n20/D 1.5396 |

Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-D-Prolinol used for?
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Z-D-Prolinol is used in chiral synthesis, peptide chemistry, chemical biology research, and as a pharmaceutical intermediate for creating complex organic molecules and APIs.
What are the CAS number and formula for Z-D-Prolinol?
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The CAS number for Z-D-Prolinol is 72597-18-3, and its empirical formula (Hill notation) is C13H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-D-Prolinol with an assay of 97%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Z-D-Prolinol be handled safely?
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Z-D-Prolinol is classified as toxic if swallowed and causes serious eye irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
Is Z-D-Prolinol a controlled substance?
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The provided data does not indicate that Z-D-Prolinol is a controlled substance.
How is Z-D-Prolinol packed, shipped, and exported?
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Z-D-Prolinol is shipped according to international regulations for hazardous materials, bearing the UN 2810 classification. Tech Serve Solutions is an experienced global exporter.
How can I request a sample or quote for Z-D-Prolinol?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team via the website or direct inquiry channels.
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