Z-D-Nle-ONp
Z-D-Nle-ONp (CAS: 31062-20-1), with the molecular formula C20H22N2O6 and a molecular weight of 386.40, is a specialised derivative within unnatural amino acid chemistry. It is a key building block and reagent employed in chemical biology and peptide synthesis. Supplied by Tech Serve Solutions, this compound is characterised by its optical activity and is typically used in research and development settings for the creation of complex peptides and modified biomolecules.
- IUPAC
- Z-D-norleucine 4-nitrophenyl ester
- Synonyms
- Z-D-norleucine 4-nitrophenyl ester
Peptide Synthesis
Z-D-Nle-ONp serves as an activated amino acid ester, facilitating the incorporation of D-norleucine into peptide chains. Its reactivity allows for efficient amide bond formation in both solution and solid-phase synthesis.
Chemical Biology Research
This compound is utilised in chemical biology to introduce non-natural amino acid residues into biomolecules for structure-function studies. It aids in probing biological pathways and developing novel therapeutic agents.
Biochemical Reagent
As a specific D-norleucine derivative, Z-D-Nle-ONp functions as a valuable reagent in various biochemical assays. It is employed in the development and validation of enzymatic assays and proteomic studies.
| Molecular weight | 386.40 |
|---|---|
| Empirical formula | C20H22N2O6 |
| Assay | ≥98.0% (calc. based on dry substance, C/N) |
| Optical activity | [α]20/D +26±1°, c = 1% in DMF |
| Storage temperature | 2-8°C |
| Melting point | 63-67 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-D-Nle-ONp used for?
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Z-D-Nle-ONp is primarily used in peptide synthesis and chemical biology research as an activated derivative for incorporating D-norleucine into peptides and biomolecules.
What is the CAS number and chemical formula for Z-D-Nle-ONp?
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The CAS number is 31062-20-1, and the chemical formula is C20H22N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-D-Nle-ONp with an assay of ≥98.0% (calculated based on dry substance, C/N). This is a research-grade chemical and is not represented as USP, BP, or EP.
How should Z-D-Nle-ONp be handled and stored?
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Handle Z-D-Nle-ONp with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 or P1 respirator filter. Store at 2-8°C to maintain its integrity.
Is Z-D-Nle-ONp a hazardous substance?
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Yes, Z-D-Nle-ONp is classified with a WGK Germany of 3, indicating it is hazardous. Adhere strictly to safety guidelines during handling and storage.
How is Z-D-Nle-ONp packed and exported?
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Z-D-Nle-ONp is carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions.
How can I request a quote or sample for Z-D-Nle-ONp?
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To request a quote or a sample of Z-D-Nle-ONp, please contact our sales team through the TSS website or designated contact channels.
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