Z-D-Leu-OH
Z-D-Leu-OH (CAS 28862-79-5), with the molecular formula C14H19NO4 and a molecular weight of 265.30, is a D-amino acid derivative crucial in peptide chemistry and synthesis. It serves as a vital building block in the construction of peptides and peptidomimetics. Its applications span chemical biology and organic synthesis, offering researchers a key intermediate for developing novel compounds with potential therapeutic or research applications.
- IUPAC
- N-Cbz-D-leucine,Z-D-leucine
- Synonyms
- N-Cbz-D-leucineZ-D-leucine

Peptide Synthesis
Z-D-Leu-OH acts as a protected amino acid derivative essential for the synthesis of peptides containing D-leucine residues. This is important for creating peptides with altered stability or biological activity compared to their L-amino acid counterparts.
Chemical Biology Research
This compound is utilised in chemical biology to investigate peptide structure-function relationships and to develop peptide-based probes or therapeutics. The incorporation of D-amino acids can significantly influence a peptide's pharmacokinetic and pharmacodynamic properties.
Organic Synthesis Intermediate
As a chiral building block, Z-D-Leu-OH finds application in the stereoselective synthesis of complex organic molecules. It enables chemists to introduce a specific D-leucine moiety into target structures.
| Molecular weight | 265.30 |
|---|---|
| Empirical formula | C14H19NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-D-Leu-OH used for?
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Z-D-Leu-OH is primarily used as a building block in peptide synthesis and as an intermediate in organic and chemical biology research, particularly for the incorporation of D-leucine into peptides and complex molecules.
What is the CAS number and molecular formula for Z-D-Leu-OH?
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The CAS number for Z-D-Leu-OH is 28862-79-5, and its molecular formula is C14H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-D-Leu-OH with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for Z-D-Leu-OH?
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For safe handling, it is recommended to wear eyeshields and gloves. Z-D-Leu-OH has a WGK Germany classification of 3, indicating it is hazardous to water.
How is Z-D-Leu-OH packed, shipped, and exported?
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Z-D-Leu-OH is carefully packed to ensure stability during transit and is available for export globally by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or quote for Z-D-Leu-OH?
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To request a sample or a quote for Z-D-Leu-OH, please contact our sales team through the TSS website, providing your specific requirements.
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