Z-D-Phg-OH
Z-D-Phg-OH (CAS: 17609-52-8), with the molecular formula C16H15NO4, is a derivative of the unnatural amino acid D-phenylglycine. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology. Its precise structure allows for the incorporation of non-proteinogenic amino acid features into peptides and other complex organic molecules, offering unique structural and functional properties for research and development applications.
- IUPAC
- Z-D-phenylglycine
- Synonyms
- Z-D-phenylglycine

Peptide Synthesis
Z-D-Phg-OH is utilised as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis. It enables the introduction of D-phenylglycine residues, which can modulate peptide conformation, stability, and biological activity.
Chemical Biology Research
In chemical biology, this compound acts as a precursor for synthesising modified peptides or peptidomimetics. These molecules can be used to probe biological pathways, develop enzyme inhibitors, or create novel therapeutic agents.
Organic Synthesis Intermediate
As a phenylglycine derivative, Z-D-Phg-OH functions as a versatile intermediate in broader organic synthesis. It can be employed in the construction of complex chiral molecules where the specific stereochemistry and functionality of phenylglycine are required.
| Molecular weight | 285.29 |
|---|---|
| Empirical formula | C16H15NO4 |
| Assay | ≥99.0% (HPLC) |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-D-Phg-OH used for?
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Z-D-Phg-OH is primarily used in peptide synthesis, chemical biology research, and as a general intermediate in organic synthesis for creating molecules with unnatural amino acid features.
What are the CAS number and molecular formula for Z-D-Phg-OH?
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The CAS number for Z-D-Phg-OH is 17609-52-8, and its molecular formula is C16H15NO4.
What grade and purity does Tech Serve Solutions supply for Z-D-Phg-OH?
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Tech Serve Solutions supplies Z-D-Phg-OH with a minimum purity of ≥99.0% (HPLC). This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Z-D-Phg-OH be handled safely?
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Z-D-Phg-OH is classified as a Warning substance. It is harmful if swallowed (H302) and causes serious eye irritation (H319). When handling, use a dust mask type N95 (US), wear eyeshields and gloves. In case of accidental eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do, continuing rinsing (P305 + P351 + P338).
Is Z-D-Phg-OH a controlled substance?
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Based on the provided data, Z-D-Phg-OH is not listed as a controlled substance.
Can Tech Serve Solutions export Z-D-Phg-OH?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Z-D-Phg-OH.
How can I request a sample or quote for Z-D-Phg-OH?
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To request a sample or a quote for Z-D-Phg-OH, please contact our sales team through the website or via email, providing your specific requirements.
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