Valsartan

CAS 137862-53-4C24H29N5O3Biochemicals & Reagents

Valsartan (CAS: 137862-53-4), with the empirical formula C24H29N5O3 and a molecular weight of 435.52 g/mol, is a selective Angiotensin II receptor antagonist. It is supplied by Tech Serve Solutions as a white to tan powder. This compound is primarily utilised in research settings to investigate the Ang II-dependent pathway and its effects, particularly in studies related to aldosterone. Its solubility in DMSO is notable, facilitating its use in various laboratory assays.

IUPAC: N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine

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Valsartan (C24H29N5O3) — chemical structure, CAS 137862-53-4; Life Science, fine chemical supplied by Tech Serve Solutions

AngiotensinsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNovartisPeptides and ProteinsPeptides for Cell Biology

01 /Applications

Research in Cardiovascular Pathways

Valsartan is employed in scientific research to study the intricate mechanisms of the Renin-Angiotensin-Aldosterone System (RAAS). Its specific action as an Angiotensin II receptor antagonist allows researchers to probe the effects of blocking this pathway on physiological processes.

Investigation of Aldosterone-Related Effects

Studies utilize valsartan to understand the role of the Ang II-dependent pathway in aldosterone secretion and its subsequent physiological consequences. For instance, animal models have been treated with valsartan to elucidate these complex interactions.

Pharmacological Tool for Receptor Studies

As a well-defined Angiotensin Receptor Blocker, valsartan serves as a valuable tool for investigating G protein-coupled receptor (GPCR) modulation and cell signaling pathways in various biological systems.

02 /Properties

Molecular weight	435.52
Empirical formula	C24H29N5O3
Assay	≥98% (HPLC)
Form	powder
Colour	white to tan
Solubility	DMSO: ≥20 mg/mL
Optical activity	[α]/D -55 to -70°, c = 1 in methanol
Storage temperature	2-8°C
Application	Mice were treated with valsartan to study the role of Ang II-dependent pathway in aldosterone-related effects.1

03 /Identifiers & registry

CAS number

137862-53-4

04 /Additional specifications

Storage Condition	desiccated

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Valsartan used for?

Valsartan (CAS: 137862-53-4) is used in scientific research, particularly for studying the Ang II-dependent pathway and aldosterone-related effects. It acts as a selective Angiotensin II receptor antagonist.

What is the CAS number and formula for Valsartan?

The CAS number for Valsartan is 137862-53-4, and its empirical formula is C24H29N5O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Valsartan with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade; it is intended for research and laboratory use.

What are the safety and handling precautions for Valsartan?

Valsartan has a WGK Germany rating of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment and avoid release into the environment.

How is Valsartan supplied and exported by TSS?

Valsartan is typically supplied as a powder and stored at 2-8°C in a desiccated state. TSS exports this chemical globally, adhering to all relevant shipping regulations.