Valinomycin

CAS 2001-95-8C54H90N6O18Biochemicals & Reagents

Valinomycin (CAS: 2001-95-8, C54H90N6O18, MW: 1111.32) is a potent ionophore antibiotic, a cyclic peptide derived from *Streptomyces* species. It functions by facilitating the transport of potassium ions across biological membranes, disrupting cellular ion gradients. This property makes it a valuable tool in biochemical research for studying membrane transport and cellular energy metabolism. It is also investigated for its potential antineoplastic and immunosuppressive properties.

IUPAC: Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid

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Valinomycin (C54H90N6O18) — chemical structure, CAS 2001-95-8; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics T-ZAntibiotics by ApplicationAntimycobacterialBioactive Small MoleculesBiochemicals and ReagentsCell BiologyChemical Structure ClassMechanism of Action

01 /Applications

Membrane Transport Studies

Valinomycin is widely used to investigate the role of potassium ion permeability in cellular processes, making it indispensable for research in cell biology and biophysics.

Biochemical Research Tool

As an ionophore, it serves as a critical reagent for studies on mitochondrial function, energy transduction, and the effects of ion imbalances on cellular activity.

Antimycobacterial Research

Its documented activity against mycobacteria makes Valinomycin a subject of interest in the development of new therapeutic strategies for related infections.

Antineoplastic and Immunosuppressive Investigations

Valinomycin exhibits cytotoxic effects and immunomodulatory potential, leading to its exploration in cancer research and the study of immune responses.

02 /Properties

Molecular weight	1111.32
Empirical formula	C54H90N6O18
Assay	≥90% (HPLC)
Concentration	~1 mg/mL in DMSO
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGI
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T+
Risk statements (R)	27/28
Safety statements (S)	28-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

2001-95-8

Beilstein registry

78657

05 /Additional specifications

Sterility	0.2 μm filtered

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Valinomycin used for?

Valinomycin is primarily used in biochemical research to study ion transport, particularly potassium ions across biological membranes, and to investigate mitochondrial function. It is also explored for its antimycobacterial, antineoplastic, and immunosuppressive properties.

What are the CAS number and formula for Valinomycin?

The CAS number for Valinomycin is 2001-95-8, and its empirical formula is C54H90N6O18.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Valinomycin with a purity of ≥90% as determined by HPLC. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Valinomycin be handled and stored?

Valinomycin is a highly toxic substance (Danger, H300 + H310). Handle with extreme caution, using appropriate personal protective equipment including eyeshields, face shields, gloves, and a suitable respirator. Store refrigerated at 2-8°C.

How is Valinomycin packed and exported?

Valinomycin is typically supplied as a solution in DMSO, filtered through a 0.2 μm filter, and stored at 2-8°C. TSS exports this chemical globally following all relevant regulations.