Trimethylene oxide
Trimethylene oxide (CAS: 503-30-0, C3H6O) is a cyclic ether with a molecular weight of 58.08 g/mol. It is a colourless liquid known for its utility as a building block in organic synthesis. This oxetane derivative is primarily employed in the development of more complex molecules within the fields of asymmetric synthesis and heterocyclic chemistry. Its specific reactivity makes it a valuable intermediate for researchers and chemists.
- IUPAC
- Oxetane

Building Block in Organic Synthesis
Trimethylene oxide serves as a versatile three-carbon synthon. It is frequently incorporated into synthetic pathways to introduce specific structural motifs, particularly in the construction of heterocyclic compounds.
Chiral Chemistry
As a chiral building block, it is utilized in asymmetric synthesis to create enantiomerically enriched products. Its structure lends itself to stereoselective transformations critical in pharmaceutical and fine chemical research.
Heterocyclic Compound Synthesis
This compound is a key intermediate for accessing various oxetane-containing heterocycles. These structures are of interest due to their presence in biologically active molecules and novel materials.
| Molecular weight | 58.08 |
|---|---|
| Empirical formula | C3H6O |
| Assay | 97% |
| Grade | purum |
| Boiling point | 50 °C(lit.) |
| Density | 0.893 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.388-1.396n20/D 1.392(lit.) |
| Vapour pressure | 5.09 psi (20 °C) |
| Storage temperature | 2-8°C |


Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -20 °C / -4 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20/21/22 |
| Safety statements (S) | 9-16-26-29 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trimethylene oxide used for?
+
Trimethylene oxide (CAS: 503-30-0, C3H6O) is used as a building block in organic synthesis, particularly in asymmetric synthesis and the creation of heterocyclic compounds.
What is the CAS number and formula for Trimethylene oxide?
+
The CAS number for Trimethylene oxide is 503-30-0, and its chemical formula is C3H6O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Trimethylene oxide with an assay of 97% and a 'purum' grade. This product is intended for research and laboratory use and is not represented as USP/BP/EP grade.
How should Trimethylene oxide be handled safely?
+
Trimethylene oxide is a flammable liquid and harmful if swallowed, inhaled, or absorbed through the skin. Handle with appropriate personal protective equipment, including gloves, eye protection, and a respirator, in a well-ventilated area. Keep away from heat and open flames. Consult the Safety Data Sheet for full details.
How is Trimethylene oxide packed and shipped?
+
Trimethylene oxide is typically packed according to industry standards for flammable liquids and shipped as UN 1993 BF 3 / PG II. We export globally; please contact us for specific shipping and handling inquiries.
How can I request a sample or quote for Trimethylene oxide?
+
To request a sample or a quote for Trimethylene oxide, please contact our sales team through the website or by phone. Please provide your specific requirements and shipping details.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis