Trifluoroacetamide
Trifluoroacetamide (CAS: 354-38-1) is an organic compound with the linear formula CF₃CONH₂ and a molecular weight of 113.04 g/mol. This fluorinated amide serves as a valuable building block in organic synthesis. Its structure, featuring a trifluoromethyl group attached to an acetamide moiety, makes it useful for introducing fluorinated functionalities into more complex molecules across various chemical research and development sectors.
Organic Synthesis Intermediate
Trifluoroacetamide functions as a key intermediate in the synthesis of various organic compounds. It is particularly useful for the preparation of fluorinated pharmaceuticals and agrochemicals, where the trifluoromethyl group can impart desirable properties such as increased metabolic stability or lipophilicity.
Reagent for Derivatization
In analytical chemistry, Trifluoroacetamide can be employed as a derivatizing agent. Its reaction with certain analytes can form derivatives that are more amenable to chromatographic separation or detection, particularly in gas chromatography.
Building Block for Fluorinated Materials
The compound's trifluoromethyl group makes it a useful starting material for developing novel fluorinated polymers and materials with unique thermal, chemical, and electrical properties.
| Molecular weight | 113.04 |
|---|---|
| Linear formula | CF3CONH2 |
| Assay | ≥97.0% (N) |
| Grade | purum |
| Boiling point | 162.5 °C(lit.) |
| Melting point | 65-70 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Trifluoroacetamide used for?
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Trifluoroacetamide (CAS: 354-38-1) is primarily used as a building block in organic synthesis, particularly for introducing trifluoromethyl groups into pharmaceuticals, agrochemicals, and other complex organic molecules. It can also serve as a derivatization reagent in analytical chemistry.
What are the CAS number and chemical formula for Trifluoroacetamide?
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The CAS number for Trifluoroacetamide is 354-38-1, and its linear chemical formula is CF₃CONH₂.
What grade and purity does Tech Serve Solutions supply for Trifluoroacetamide?
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Tech Serve Solutions supplies Trifluoroacetamide with a minimum purity of 97.0% (N), meeting the 'purum' grade. We do not represent this product as USP, BP, or EP grade.
How should Trifluoroacetamide be handled safely?
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Trifluoroacetamide is classified with Warning signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). When handling, use a dust mask type N95 (US), wear eyeshields and gloves, and ensure adequate ventilation. P261 and P305 + P351 + P338 precautionary statements should be followed.
Is Trifluoroacetamide a controlled substance?
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Based on the provided data, Trifluoroacetamide is not indicated as a controlled substance.
How is Trifluoroacetamide packed and shipped globally by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and Trifluoroacetamide is available for international shipment, adhering to all relevant shipping regulations.
How can I request a quote or sample of Trifluoroacetamide?
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To request a quote or a sample of Trifluoroacetamide, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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