Tioconazole

CAS 65899-73-2C16H13Cl3N2OSBiochemicals & Reagents

Tioconazole (CAS 65899-73-2), a halogenated imidazole derivative with the formula C16H13Cl3N2OS and a molecular weight of 387.71 g/mol, is an antifungal agent. It functions by disrupting fungal cell membrane permeability. Tioconazole is primarily utilized in research for studying antifungal mechanisms and drug interactions, particularly concerning yeast infections like those caused by Candida albicans.

IUPAC: 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole,Thioconazole

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Tioconazole (C16H13Cl3N2OS) — chemical structure, CAS 65899-73-2; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics T-ZAntifungalBiochemicals and ReagentsChemical Structure ClassMechanism of ActionPyridines and PyrimidinesSpectrum of Activity More...

01 /Applications

Antifungal Research

Tioconazole is used in laboratory settings to investigate the efficacy and mechanisms of antifungal treatments. Its imidazole structure makes it a valuable tool for studying drug resistance and synergistic effects with other antimicrobial agents.

Drug Interaction Studies

This compound serves as a model for exploring drug-drug interactions in vivo and in vitro. Researchers utilize Tioconazole to understand how it interacts with other medications, contributing to pharmacodynamic and pharmacokinetic research.

Candida albicans Studies

Tioconazole is employed to study its effects on Candida albicans, a common yeast pathogen. This research helps in understanding antifungal susceptibility and developing new therapeutic strategies against fungal infections.

02 /Properties

Molecular weight	387.71
Empirical formula	C16H13Cl3N2OS
Assay	≥96.5% (HPLC)96.5-103.5% (NT)97%
Application	Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast. It is used to study the synergistic mechanisms of antifungals on Candida albicans 1 as well as significant drug-drug interactions in vivo2.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H413May cause long-lasting harmful effects to aquatic life

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

65899-73-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Tioconazole used for?

Tioconazole is used in research to study antifungal mechanisms, particularly against fungi like Candida albicans, and to investigate drug-drug interactions.

What is the CAS number and formula for Tioconazole?

The CAS number for Tioconazole is 65899-73-2, and its empirical formula is C16H13Cl3N2OS.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tioconazole with an assay of ≥96.5% by HPLC, 96.5-103.5% by NT, and 97%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations for Tioconazole?

Tioconazole is classified with the GHS07 symbol and has a 'Warning' signal word. It carries hazard statements H302 (Harmful if swallowed) and H413 (May cause long lasting harmful effects to aquatic life). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used when handling.

How is Tioconazole shipped and exported?

Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Tioconazole, adhering to all relevant shipping and export regulations.