Tizanidine hydrochloride
Tizanidine hydrochloride (CAS 64461-82-1), a white powder with the molecular formula C9H9Cl2N5S and a molecular weight of 290.17, is an alpha-2 adrenergic agonist. It functions as a skeletal muscle relaxant. TSS supplies this compound with an assay of ≥98% (HPLC), suitable for research and development applications. Its solubility in water is greater than 20 mg/mL.
- IUPAC
- 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride
Spectrophotometric Method Development
Tizanidine hydrochloride has been utilized in the development of spectrophotometric methods for the validation of skeletal muscle relaxants. This application focuses on analytical chemistry and method validation in pharmaceutical analysis.
Adrenergic Receptor Research
As an alpha-2 adrenergic agonist, Tizanidine hydrochloride serves as a valuable tool for researchers investigating adrenergic receptor pathways and their physiological roles. It is particularly relevant in neuroscience and cell signaling studies.
Skeletal Muscle Relaxant Studies
The compound's primary pharmacological action as a muscle relaxant makes it a subject of interest in studies related to spasticity and muscle tone. This includes research into its mechanism of action at the molecular level.
| Molecular weight | 290.17 |
|---|---|
| Empirical formula | C9H9Cl2N5S |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: >20 mg/mL |
| Application | Tizanidine hydrochloride has been used for developing spectrophotometric methods for the validation of skeletal muscle relaxants1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tizanidine hydrochloride used for?
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Tizanidine hydrochloride is used in the development of analytical methods for skeletal muscle relaxants and for research into alpha-2 adrenergic agonist activity, particularly in neuroscience and cell signaling.
What are the CAS number and molecular formula for Tizanidine hydrochloride?
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The CAS number for Tizanidine hydrochloride is 64461-82-1, and its empirical formula is C9H9Cl2N5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tizanidine hydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety considerations when handling Tizanidine hydrochloride?
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Tizanidine hydrochloride is a Warning substance (GHS07) that may cause respiratory irritation, skin irritation, and serious eye irritation (H315-H319-H335), and is harmful if swallowed (H302). Appropriate personal protective equipment, including dust masks (N95), eyeshields, faceshields, and gloves, should be worn. Handle in a well-ventilated area.
How is Tizanidine hydrochloride packed, shipped, and exported?
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Tizanidine hydrochloride is carefully packed in appropriate containers to maintain its integrity during transit. Tech Serve Solutions has extensive experience in global exporting of fine chemicals, adhering to all relevant shipping regulations.
How can I request a sample or quote for Tizanidine hydrochloride?
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To request a sample or a quote for Tizanidine hydrochloride, please contact our sales team through the website or by phone. Please specify the required quantity and any particular specifications.
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