Tetramethyl orthocarbonate
Tetramethyl orthocarbonate (CAS: 1850-14-2), with the molecular formula C(OCH3)4 and a molecular weight of 136.15 g/mol, is a chemical compound primarily utilised as an organic building block in synthesis. It belongs to the class of orthoesters and finds applications in various chemical processes. Supplied by Tech Serve Solutions, this reagent is available for research and industrial applications.

Organic Synthesis Reagent
Tetramethyl orthocarbonate serves as a versatile reagent in organic synthesis. Its structure allows it to act as a source of the tetracarbonyl unit or as a methoxy group transfer agent in various chemical transformations.
Building Block for Complex Molecules
As an organic building block, this compound is employed in the construction of more complex molecular architectures. It is particularly useful in the synthesis of heterocycles and other specialised organic compounds.
Intermediate in Chemical Manufacturing
This orthoester can function as an intermediate in the production of various fine chemicals and pharmaceutical precursors. Its reactivity profile makes it suitable for specific synthetic routes.
| Molecular weight | 136.15 |
|---|---|
| Linear formula | C(OCH3)4 |
| Assay | ≥97.0% (GC) |
| Boiling point | 114 °C(lit.) |
| Density | 1.023 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.385(lit.)n20/D 1.385 |
| Melting point | −5 °C(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 22 °C / 71.6 °F |
| Transport (UN / ADR) | UN 3272 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethyl orthocarbonate used for?
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Tetramethyl orthocarbonate is used as a reagent and building block in organic synthesis, and as an intermediate in chemical manufacturing.
What are the CAS number and formula for Tetramethyl orthocarbonate?
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The CAS number for Tetramethyl orthocarbonate is 1850-14-2, and its linear formula is C(OCH3)4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethyl orthocarbonate with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Tetramethyl orthocarbonate be handled safely?
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Tetramethyl orthocarbonate is a flammable liquid and vapour (H225) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive guidance.
How is Tetramethyl orthocarbonate packed and shipped?
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Tetramethyl orthocarbonate is typically packed and shipped as UN 3272, Class 3, Packing Group II, adhering to regulations for flammable liquids.
How can I request a sample or quote for Tetramethyl orthocarbonate?
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To request a sample or quote for Tetramethyl orthocarbonate, please contact our sales team via the website or by telephone.
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