Strophanthidin
Strophanthidin (CAS 66-28-4), with the molecular formula C23H32O6 and a molecular weight of 404.50 g/mol, is a cardiac glycoside and a steroidal lactone. It serves as a key intermediate in biochemical research, particularly in studies concerning neurotransmitter release and the synthesis of related compounds. Its steroidal structure also places it within the lipid and organic building block categories for chemical synthesis.
- IUPAC
- 3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide,Cymarigenen,K-Strophanthidin

Biochemical Research
Strophanthidin is employed in scientific investigations to explore its pharmacological effects and biochemical pathways. It has been utilised in studies concerning neurotransmitter release mechanisms in biological systems.
Chemical Synthesis
As an organic building block, Strophanthidin can be used as a starting material or intermediate in the synthesis of more complex organic molecules. Its steroidal structure makes it valuable for creating derivatives with potential biological activity.
Intermediate for Derivatives
Research involving Strophanthidin has included its use in the synthesis of related compounds, such as acetylstrophanthidin. Such derivatives are often studied for modified or enhanced biological properties.
| Molecular weight | 404.50 |
|---|---|
| Empirical formula | C23H32O6 |
| Assay | ≥90% |
| Solubility | ethanol: complete50 mg/mL, clear, colorless |
| Storage temperature | −20°C |
| Application | Strophanthidin was used to synthesize acetylstrophanthidin and the effect on neurotransmitter release from dog saphenous vein was studied.3 |

Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28 |
| Safety statements (S) | 22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Strophanthidin used for?
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Strophanthidin is used in biochemical research, for the synthesis of derivatives like acetylstrophanthidin, and as an organic building block in chemical synthesis.
What is the CAS number and formula for Strophanthidin?
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The CAS number for Strophanthidin is 66-28-4, and its empirical formula is C23H32O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Strophanthidin with an assay of ≥90%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Strophanthidin be handled safely?
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Strophanthidin is a highly toxic substance. Handle with extreme caution, using appropriate personal protective equipment including eyeshields, faceshields, gloves, and a full-face particle respirator (type N100 US or P3 EN143). Avoid inhalation, ingestion, and skin contact. It is classified as Danger (GHS06) with hazards H300, H310, and H330.
Is Strophanthidin a controlled substance?
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The provided data does not indicate that Strophanthidin is a controlled substance. However, its high toxicity requires strict adherence to safety protocols during handling and use.
How is Strophanthidin packed and shipped?
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Strophanthidin is shipped under UN 2811, Hazard Class 6.1, Packing Group I, indicating it is a toxic solid. For detailed shipping and handling information, please contact TSS.
How can I request a quote or sample for Strophanthidin?
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To request a quote or sample for Strophanthidin, please contact Tech Serve Solutions directly through our website or designated sales channels.
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