4-Fmoc-1-piperazineacetic acid hydrate
Tech Serve Solutions offers 4-Fmoc-1-piperazineacetic acid hydrate (CAS: 180576-05-0, C21H22N2O4 · xH2O). This compound has a molecular weight of 366.41 g/mol (anhydrous basis). Primarily utilised in chemical synthesis and peptide chemistry, it serves as a valuable building block. Its structure makes it suitable for modifications in drug discovery and the development of unnatural amino acid derivatives. Available from TSS with an assay of ≥97.0%.
- IUPAC
- 4-Fmoc-piperazin-1-ylacetic acid
- Synonyms
- 4-Fmoc-piperazin-1-ylacetic acid

Peptide Synthesis
This compound is employed as a protected amino acid derivative in solid-phase peptide synthesis (SPPS) and solution-phase methods. It allows for the controlled incorporation of modified piperazine moieties into peptide sequences.
Chemical Synthesis
Its reactive functional groups make it a versatile intermediate for constructing more complex organic molecules. It can be used in the development of novel chemical entities for research purposes.
Drug Discovery
As a building block in medicinal chemistry, it aids in the synthesis of potential therapeutic agents. The piperazine core is a common feature in many pharmacologically active compounds.
Unnatural Amino Acid Derivatives
It serves as a precursor for creating non-proteinogenic amino acids, expanding the scope of peptide and protein research and engineering.
| Molecular weight | 366.41 (anhydrous basis) |
|---|---|
| Empirical formula | C21H22N2O4 · xH2O |
| Assay | ≥97.0% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fmoc-1-piperazineacetic acid hydrate used for?
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This compound is primarily used in chemical synthesis, peptide chemistry, drug discovery, and as a building block for unnatural amino acid derivatives. It is a protected amino acid derivative suitable for peptide synthesis.
What is the CAS number and formula for 4-Fmoc-1-piperazineacetic acid hydrate?
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The CAS number is 180576-05-0, and the empirical formula is C21H22N2O4 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Fmoc-1-piperazineacetic acid hydrate with an assay of ≥97.0%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-Fmoc-1-piperazineacetic acid hydrate be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK-Germany 3, indicating a high hazard to water.
How is 4-Fmoc-1-piperazineacetic acid hydrate shipped?
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This product is typically stored at 2-8°C and is carefully packed and exported by Tech Serve Solutions, adhering to all necessary regulations for chemical transport.
How can I request a quote or sample?
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To request a quote or sample of 4-Fmoc-1-piperazineacetic acid hydrate, please contact the Tech Serve Solutions sales team via our website or direct inquiry.
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