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4-Fluorotoluene

CAS 352-32-9CH3C6H4FChemical Synthesis

4-Fluorotoluene (CAS 352-32-9), a fluorinated aromatic hydrocarbon with the formula CH3C6H4F, is a valuable building block in organic synthesis. Possessing a molecular weight of 110.13 g/mol, this compound is frequently employed in the development of pharmaceuticals, agrochemicals, and advanced materials. Its reactive methyl group and the presence of fluorine on the aromatic ring offer versatile synthetic pathways for chemists seeking to introduce specific functionalities into target molecules.

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4-Fluorotoluene (CH3C6H4F) — chemical structure, CAS 352-32-9; Chemistry, fine chemical supplied by Tech Serve Solutions
ArylBuilding BlocksC7-C8Chemical SynthesisFluorinated Building BlocksHalogenated HydrocarbonsOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediates

4-Fluorotoluene serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates. Its fluorinated structure can enhance metabolic stability and binding affinity of drug molecules.

Agrochemical Development

The compound is utilised in the creation of novel pesticides, herbicides, and fungicides. The incorporation of fluorine can modify the biological activity and environmental persistence of agrochemicals.

Materials Science

It finds application in the synthesis of specialty polymers and functional materials where the unique electronic properties imparted by the fluorine atom are advantageous.

Research and Development

As a versatile building block, 4-Fluorotoluene is widely used in academic and industrial research labs for exploring new chemical reactions and synthesising novel organic compounds.

02 /Properties
Molecular weight110.13
Linear formulaCH3C6H4F
Assay97%
Boiling point116 °C(lit.)
Density1 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.468(lit.)
Melting point−56 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H302Harmful if swallowed
  • H312Harmful in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point10 °C / 50 °F
Transport (UN / ADR)UN 2388 3 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xn
Risk statements (R)11-20/21/22
Safety statements (S)7-16-36/37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
352-32-9
MDL number
MFCD00000358
PubChem substance
24894781
Beilstein registry
1362373
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Fluorotoluene used for?

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4-Fluorotoluene is primarily used as a building block in organic synthesis, particularly for developing pharmaceuticals, agrochemicals, and advanced materials. It is also a common reagent in research and development laboratories.

What are the CAS number and chemical formula for 4-Fluorotoluene?

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The CAS number for 4-Fluorotoluene is 352-32-9, and its chemical formula is CH3C6H4F.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Fluorotoluene with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should 4-Fluorotoluene be handled safely?

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4-Fluorotoluene is flammable and harmful if swallowed, inhaled, or in contact with skin, and causes skin and serious eye irritation. Handle with appropriate personal protective equipment, including gloves, eyeshields, and a suitable respirator, in a well-ventilated area. Refer to the safety data sheet for comprehensive handling information.

How is 4-Fluorotoluene packed and shipped?

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4-Fluorotoluene is packed according to international safety standards for hazardous materials, including UN 2388 classification. Tech Serve Solutions is an experienced global exporter.

How can I request a quote or sample for 4-Fluorotoluene?

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To request a quote or sample of 4-Fluorotoluene, please contact our sales team through the website or by phone. Provide your details and the quantity required.

Need 4-Fluorotoluene in a specific grade or volume?