4-Fluorothiophenol
4-Fluorothiophenol (CAS 371-42-6), with the molecular formula C6H5FS, is a fluorinated aromatic thiol. This compound serves as a valuable building block in organic synthesis. Its unique structure, featuring both a fluorine atom and a thiol group on a benzene ring, allows for diverse chemical transformations. It is primarily utilised in the development of novel materials and pharmaceutical intermediates by researchers and chemical manufacturers.
- IUPAC
- 4-Mercaptofluorobenzene,4-Fluorobenzenethiol
- Synonyms
- 4-Mercaptofluorobenzene4-Fluorobenzenethiol
Organic Synthesis Intermediate
4-Fluorothiophenol is employed as a key intermediate in the synthesis of complex organic molecules. Its reactive thiol group readily participates in various coupling reactions and nucleophilic substitutions.
Pharmaceutical Research
This compound is utilised in medicinal chemistry for the preparation of potential drug candidates. The introduction of a fluorothiophenyl moiety can modulate the pharmacokinetic and pharmacodynamic properties of bioactive molecules.
Material Science
It can be used in the development of functional materials. The presence of fluorine can impart desirable properties such as thermal stability and altered electronic characteristics.
| Molecular weight | 128.17 |
|---|---|
| Linear formula | FC6H4SH |
| Assay | ≥97.0% (GC) |
| Grade | purum |
| Boiling point | 164-168 °C |
| Density | 1.203 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.550(lit.)n20/D 1.550 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 54 °C / 129.2 °F |
| Transport (UN / ADR) | UN 3336 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Fluorothiophenol used for?
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4-Fluorothiophenol is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and material science due to its fluorinated aromatic thiol structure.
What is the CAS number and chemical formula for 4-Fluorothiophenol?
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The CAS number is 371-42-6 and the chemical formula is FC6H4SH.
What grade and purity does Tech Serve Solutions supply for 4-Fluorothiophenol?
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Tech Serve Solutions supplies 4-Fluorothiophenol with a purity of ≥97.0% (GC), designated as purum grade. This product is not represented as USP, BP, or EP grade.
How should 4-Fluorothiophenol be handled safely?
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4-Fluorothiophenol is a flammable liquid and vapour (H226), and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area.
Is 4-Fluorothiophenol a controlled substance?
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The provided data does not indicate that 4-Fluorothiophenol is a controlled substance.
How is 4-Fluorothiophenol packed and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions packs and exports chemicals like 4-Fluorothiophenol according to relevant international shipping regulations for hazardous materials (UN 3336, Class 3).
How can I request a quote or sample of 4-Fluorothiophenol?
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To request a quote or sample of 4-Fluorothiophenol, please contact our sales team through the TSS website or by phone.
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