SR 27897 hydrate

CAS 136381-85-6 (anhydrous)C20H14ClN3O3S · xH2OBiochemicals & Reagents

SR 27897 hydrate (CAS: 136381-85-6), a Cholecystokinin (CCK) receptor antagonist, is identified by its molecular formula C20H14ClN3O3S · xH2O and a molecular weight of 411.86 g/mol on an anhydrous basis. This bioactive small molecule is supplied as a white to tan powder. It is primarily utilised in research settings to investigate CCK1-mediated cell signaling pathways, contributing to advancements in neuroscience and cell biology research.

IUPAC: 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid hydrate

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SR 27897 hydrate (C20H14ClN3O3S · xH2O) — chemical structure, CAS 136381-85-6 (anhydrous); Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyCholecystokininsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuropeptidesPeptides and ProteinsPeptides for Cell Biology

01 /Applications

Neuroscience Research

SR 27897 hydrate serves as a valuable tool for studying the role of cholecystokinin receptors in the central nervous system. It aids in understanding neuropeptide signaling and its impact on neuronal function and behaviour.

Cell Signaling Studies

This compound is employed to investigate CCK1 receptor-mediated intracellular signaling cascades. Researchers use it to elucidate downstream effects in various cell types, contributing to cell biology and pharmacology.

Drug Discovery and Development

As an antagonist of CCK receptors, SR 27897 hydrate can be used in preclinical research for the development of therapeutics targeting conditions modulated by CCK signaling.

02 /Properties

Molecular weight	411.86 (anhydrous basis)
Empirical formula	C20H14ClN3O3S · xH2O
Assay	≥98% (HPLC)
Form	powder
Colour	white to tan
Solubility	DMSO: ≥10 mg/mL at warmed to 60 °C
Storage temperature	2-8°C
Application	SR 27897 hydrate may be used to study CCK1-mediated cell signaling.

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed
H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P301IF SWALLOWED
P305IF IN EYES

Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25-41
Safety statements (S)	26-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

136381-85-6 (anhydrous)

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SR 27897 hydrate used for?

SR 27897 hydrate is primarily used in research to study CCK1-mediated cell signaling and as a cholecystokinin receptor antagonist.

What are the CAS number and formula for SR 27897 hydrate?

The CAS number for the anhydrous form is 136381-85-6, and the empirical formula is C20H14ClN3O3S · xH2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SR 27897 hydrate with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should SR 27897 hydrate be handled and stored?

SR 27897 hydrate is classified as Dangerous Goods (UN 2811, 6.1/PGIII) with GHS hazard statements H301 and H318, requiring careful handling. Store desiccated at 2-8°C.