Sodium thioglycolate
Sodium thioglycolate (CAS 367-51-1), with the linear formula HSCH₂COONa and a molecular weight of 114.10 g/mol, is a key organosulfur compound. It is recognised for its reducing properties, stemming from the reactive thiol group. Commonly employed in biochemical research and as a laboratory reagent, it serves various applications where controlled reduction or a source of sulfhydryl groups is required. Tech Serve Solutions supplies this compound with a purity of ≥96.5%.
- IUPAC
- Mercaptoacetic acid sodium salt,Thioglycolic acid sodium salt
- Synonyms
- Mercaptoacetic acid sodium saltThioglycolic acid sodium salt
Biochemical Research
Sodium thioglycolate is utilised as a reducing agent in various biochemical assays and experiments. Its ability to cleave disulfide bonds makes it valuable for protein studies and maintaining protein structure in solution.
Laboratory Reagent
As a versatile laboratory reagent, it finds application in synthetic chemistry and analytical procedures. Its properties are beneficial for specific organic transformations and as a component in certain testing methodologies.
Disulfide Bond Reduction
This compound is effective in reducing disulfide bonds within proteins and peptides. This application is crucial in biochemistry for unfolding proteins or preparing them for further analysis.
| Molecular weight | 114.10 |
|---|---|
| Linear formula | HSCH2COONa |
| Assay | ≥96.5% (iodometric) |
| Storage temperature | −20°C |
| Melting point | >300 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-38 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium thioglycolate used for?
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Sodium thioglycolate is primarily used in biochemical research as a reducing agent and in general laboratory applications. It is effective for reducing disulfide bonds in proteins and peptides.
What are the CAS number and chemical formula for Sodium thioglycolate?
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The CAS number for Sodium thioglycolate is 367-51-1, and its linear chemical formula is HSCH₂COONa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium thioglycolate with an assay of ≥96.5% (iodometric). We do not represent this product as USP, BP, or EP grade.
How should Sodium thioglycolate be handled safely?
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Sodium thioglycolate is harmful if swallowed, causes skin irritation, and causes serious eye irritation. When handling, wear a dust mask (type N95 US), safety eyeshields, and gloves. Ensure good ventilation. In case of eye contact, rinse cautiously with water for several minutes. If swallowed, call a POISON CENTER or doctor if you feel unwell.
How is Sodium thioglycolate typically packed and shipped?
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Sodium thioglycolate is stored at -20°C. TSS ensures appropriate packaging for safe handling, storage, and export according to international regulations.
How can I request a quote or sample for Sodium thioglycolate?
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To request a quote or sample of Sodium thioglycolate, please contact our sales department through the website or by phone, providing your specific requirements.
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