Semicarbazide
Semicarbazide (CAS 57-56-7), with the molecular formula H₂NCONHNH₂ and a molar mass of 75.07 g/mol, is a versatile chemical compound. It is widely recognised for its utility as an analytical reagent and in chemical synthesis. Commonly supplied as 6 wt. % on silica gel, it serves as a valuable derivatization reagent, particularly in HPLC and fluorescence applications, and acts as a scavenger in various chemical processes.
- Synonyms
- Aminourea

Analytical Reagent
Semicarbazide is employed as an analytical reagent due to its ability to react with carbonyl compounds, aiding in their identification and quantification. It is particularly useful in derivatization for chromatographic analysis.
Chemical Synthesis
This compound serves as a building block in organic synthesis, enabling the formation of semicarbazones and related structures. Its inclusion in solid-supported synthesis methodologies offers advantages in reaction work-up and product isolation.
Derivatization Agent
It is widely used as a derivatization reagent, especially for aldehydes and ketones, to enhance detectability in techniques such as HPLC and fluorescence spectroscopy, facilitating the analysis of complex mixtures.
Scavenger Applications
Semicarbazide functions as an effective scavenger, useful for removing reactive carbonyl species from reaction mixtures, thereby improving reaction selectivity and product purity.
| Molecular weight | 75.07 |
|---|---|
| Linear formula | H2NCONHNH2 |
| Composition | , 6 wt. % (on silica gel) |
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Semicarbazide used for?
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Semicarbazide (CAS 57-56-7) is primarily used as an analytical reagent and in chemical synthesis. It is a key derivatization reagent for aldehydes and ketones, especially in HPLC and fluorescence analysis, and also acts as a scavenger.
What are the CAS number and chemical formula for Semicarbazide?
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The CAS number for Semicarbazide is 57-56-7, and its linear chemical formula is H₂NCONHNH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies Semicarbazide as 6 wt. % on silica gel. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated otherwise in the product specifications.
What are the safety and handling precautions for Semicarbazide?
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Semicarbazide is classified with hazard code Xn (Harmful) in Europe, with risk statement R22 (Harmful if swallowed). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves, should be worn when handling. Ensure good ventilation.
How is Semicarbazide packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ensures that Semicarbazide is packed and shipped in compliance with all relevant international regulations for chemical transport.
How can I request a sample or a quote for Semicarbazide?
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To request a sample or a quote for Semicarbazide, please contact our sales team via the details provided on the Tech Serve Solutions website. We are happy to assist with your specific requirements.
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