sec-Butylmagnesium chloride solution
sec-Butylmagnesium chloride solution (CAS: 15366-08-2), with the linear formula CH3CH2CH(CH3)MgCl and a molecular weight of 116.87 g/mol, is a highly reactive organometallic compound. Supplied as a 2.0 M solution in diethyl ether, it serves as a versatile Grignard reagent. Its potent nucleophilic and basic properties make it essential in organic synthesis for forming new carbon-carbon bonds and as a strong base in various chemical transformations.

Carbon-Carbon Bond Formation
As a Grignard reagent, sec-Butylmagnesium chloride solution readily adds to carbonyl compounds (aldehydes, ketones, esters) and other electrophiles, facilitating the construction of complex organic molecules.
Organic Synthesis Intermediate
This compound is a key building block in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals, enabling the introduction of the sec-butyl group into target molecules.
Strong Base in Organic Reactions
Beyond its nucleophilic addition capabilities, its strong basicity allows it to be used for deprotonation reactions in various organic transformations.
| Molecular weight | 116.87 |
|---|---|
| Linear formula | CH3CH2CH(CH3)MgCl |
| Density | 0.828 g/mL at 25 °C |
| Concentration | 2.0 M in diethyl ether |



Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H260In contact with water releases flammable gases
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H336May cause drowsiness or dizziness
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P223Do not allow contact with water
- P231Handle under inert gas
- P370In case of fire
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -40 °C / -40 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 1 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-22-34-67 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is sec-Butylmagnesium chloride solution used for?
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sec-Butylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis for forming carbon-carbon bonds and as a strong base in various chemical transformations.
What is the CAS number and formula for sec-Butylmagnesium chloride solution?
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The CAS number is 15366-08-2, and its linear formula is CH3CH2CH(CH3)MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies sec-Butylmagnesium chloride solution at a concentration of 2.0 M in diethyl ether. This product is intended for laboratory and industrial synthesis and is not represented as USP/BP/EP grade.
How should sec-Butylmagnesium chloride solution be handled safely?
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This compound is highly flammable (flash point -40 °C) and reacts violently with water, releasing flammable gas. It is corrosive and can cause severe skin burns and eye damage. Handle under an inert atmosphere, away from ignition sources and water. Use appropriate personal protective equipment including gloves, eye protection, and respiratory protection.
How is sec-Butylmagnesium chloride solution packed and shipped?
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sec-Butylmagnesium chloride solution is typically packed in appropriate containers for reactive liquids and shipped according to international regulations for hazardous materials. As a specialist global supplier, TSS ensures compliant export procedures.
How can I request a quote or sample of sec-Butylmagnesium chloride solution?
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To request a quote or sample, please use the 'Request Quote' or 'Request Sample' buttons on the product page or contact our sales team directly.
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