sec-Butyllithium solution
sec-Butyllithium solution (CAS: 598-30-1, Formula: CH3CH2CH(CH3)Li) is a highly reactive organolithium reagent with a molecular weight of 64.06 g/mol. Supplied as a 1.4 M solution in cyclohexane, it is a strong base and nucleophile. This chemical is primarily utilised in organic synthesis for deprotonation reactions, as an initiator for anionic polymerisation, and in various organometallic transformations. Its potent reactivity necessitates careful handling under inert conditions.
- IUPAC
- Lithium-2-butanide,s-BuLi
Organometallic Synthesis
sec-Butyllithium serves as a potent base for deprotonation reactions in organic synthesis. It is frequently employed to generate carbanions and other reactive intermediates for further transformations.
Anionic Polymerization Initiator
This organolithium compound is a key initiator for anionic polymerization processes. It is particularly useful in the controlled synthesis of various polymers, enabling precise control over molecular weight and architecture.
Deprotonation Agent
Its strong basicity makes sec-butyllithium an effective reagent for the deprotonation of a wide range of organic substrates. This is crucial for preparing organometallic species and facilitating subsequent coupling reactions.
| Molecular weight | 64.06 |
|---|---|
| Linear formula | CH3CH2CH(CH3)Li |
| Density | 0.769 g/mL at 25 °C |
| Concentration | 1.4 M in cyclohexane |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H250Catches fire spontaneously if exposed to air
- H260In contact with water releases flammable gases
- H304May be fatal if swallowed and enters airways
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H336May cause drowsiness or dizziness
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P223Do not allow contact with water
- P231Handle under inert gas
- P370In case of fire
- P422
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3394 4.2/PG 1 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C,N |
| Risk statements (R) | 11-14/15-20-34-50/53-65 |
| Safety statements (S) | 26-36/37/39-43-45-61-62 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is sec-Butyllithium solution primarily used for?
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sec-Butyllithium solution is primarily used in organic synthesis for deprotonation reactions, as an initiator for anionic polymerization, and in organometallic transformations.
What is the CAS number and chemical formula for sec-Butyllithium solution?
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The CAS number is 598-30-1 and the linear chemical formula is CH3CH2CH(CH3)Li.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies sec-Butyllithium solution at a concentration of 1.4 M in cyclohexane. We do not claim USP, BP, or EP grades unless explicitly stated; this product is suitable for research and general laboratory applications.
How should sec-Butyllithium solution be handled safely?
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sec-Butyllithium solution is highly flammable, pyrophoric, corrosive, and toxic. It reacts violently with water and air, and can cause severe burns. Handling requires strict inert atmosphere techniques, appropriate personal protective equipment including flame-retardant clothing, gloves, eye protection, and respiratory protection.
Is sec-Butyllithium solution shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including sec-Butyllithium solution, adhering to all relevant shipping regulations.
How can I request a sample or quote for sec-Butyllithium solution?
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Please contact our sales team via our website or by phone to request a sample or a formal quotation for sec-Butyllithium solution.
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