p-Toluenesulfonic acid monohydrate
p-Toluenesulfonic acid monohydrate (CAS 6192-52-5), with the molecular formula CH₃C₆H₄SO₃H · H₂O and a molecular weight of 190.22 g/mol, is a strong organic acid. It is widely employed as an acidic catalyst in various organic syntheses, including esterifications, acetalisations, and polymerisations. Its solid, crystalline form and good solubility in polar solvents make it a convenient and effective reagent in laboratory and industrial settings.
- IUPAC
- Benzenesulfonic acid, 4-methyl-, monohydrate (9CI) p-Toluenesulfonic acid, monohydrate (8CI) 4-Methylbenzenesulfonic acid monohydrate 4-Toluenesulfonic acid monohydrate Tosic acid monohydrate
- Synonyms
- Benzenesulfonic acid, 4-methyl-, monohydrate (9CI)p-Toluenesulfonic acid, monohydrate (8CI)4-Methylbenzenesulfonic acid monohydrate4-Toluenesulfonic acid monohydrateTosic acid monohydrate

Acid Catalyst
p-Toluenesulfonic acid monohydrate serves as an effective acid catalyst in numerous organic reactions. It is particularly useful for esterification, transesterification, and acetalisation reactions, facilitating product formation under moderate conditions.
Dehydrating Agent
Due to its hygroscopic nature and strong acidity, it can act as a dehydrating agent in certain reactions, promoting equilibrium shifts towards product formation by removing water.
Curing Agent for Resins
This compound is utilised as a curing agent for various resins and polymers. Its acidic properties help initiate and accelerate the polymerisation or cross-linking processes required for material hardening.
Organic Synthesis Reagent
As a versatile synthetic reagent, p-Toluenesulfonic acid monohydrate is employed in a broad range of organic transformations, including alkylations and rearrangements, owing to its strong acidic character.
| Molecular weight | 190.22 |
|---|---|
| Linear formula | CH3C6H4SO3H · H2O |
| Assay | ≥98.5% |
| Vapour density | 5.9 (vs air) |
| Impurities tested | 9.5-11.5% water |
| Melting point | 103-106 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2585 8/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
| Cation traces | Fe: ≤0.01%Na: ≤0.002%heavy metals (as Pb): ≤0.001% |
| Anion traces | sulfate (SO42-): ≤0.3% |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Clarity Of Soln | passes test |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Toluenesulfonic acid monohydrate used for?
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p-Toluenesulfonic acid monohydrate is primarily used as an acidic catalyst in organic synthesis for reactions such as esterification and acetalisation, and as a curing agent for resins.
What are the CAS number and formula for p-Toluenesulfonic acid monohydrate?
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The CAS number is 6192-52-5, and its molecular formula is CH₃C₆H₄SO₃H · H₂O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Toluenesulfonic acid monohydrate with an assay of ≥98.5%, containing 9.5-11.5% water. We do not represent this product as USP, BP, or EP grade.
How should p-Toluenesulfonic acid monohydrate be handled?
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p-Toluenesulfonic acid monohydrate is a warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes.
Is p-Toluenesulfonic acid monohydrate shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including p-Toluenesulfonic acid monohydrate.
How can I request a quote or sample?
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To request a quote or sample of p-Toluenesulfonic acid monohydrate, please contact our sales team through the website or by phone.
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